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Pronunciation |
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(proe
METH a zeen & fen il EF
rin) |
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U.S. Brand
Names |
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Phenergan® VC Syrup; Promethazine VC Plain
Syrup; Promethazine VC Syrup; Prometh VC Plain Liquid |
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Generic
Available |
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Yes |
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Synonyms |
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Phenylephrine and Promethazine |
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Pharmacological Index |
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Antihistamine/Decongestant Combination |
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Use |
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Temporary relief of upper respiratory symptoms associated with allergy or the
common cold |
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Pregnancy Risk
Factor |
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C |
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Usual Dosage |
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Oral:
2-6 years: 1.25 mL every 4-6 hours, not to exceed 7.5 mL in 24 hours
6-12 years: 2.5 mL every 4-6 hours, not to exceed 15 mL in 24 hours
Children >12 years and Adults: 5 mL every 4-6 hours, not to exceed 30 mL
in 24 hours |
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Dietary
Considerations |
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Increase dietary intake of riboflavin |
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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Phenylephrine: Use with caution since phenylephrine is a sympathomimetic
amine which could interact with epinephrine to cause a pressor response
Promethazine: No information available to require special precautions
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Dental Health:
Effects on Dental Treatment |
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Phenylephrine: Up to 10% of patients could experience tachycardia,
palpitations, and dry mouth; use vasoconstrictor with caution
Although promethazine is a phenothiazine derivative, extrapyramidal reactions
or tardive dyskinesias are not seen with the use of this drug.
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Patient
Information |
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See individual agents. Pregnancy/breast-feeding precautions: Inform
prescriber if you are or intend to get pregnant. Breast-feeding is not
recommended. |
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Nursing
Implications |
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May cause drowsiness |
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Dosage Forms |
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Liquid: Promethazine hydrochloride 6.25 mg and phenylephrine hydrochloride 5
mg per 5 mL (120 mL, 240 mL, 473 mL) |
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