Yes

Antihistamine/Decongestant/Antitussive

Temporary relief of coughs and upper respiratory symptoms including nasal congestion

C-V

C

Oral:

<2 years: Not recommended

2 to 6 years:

Weight 25 lb: 1.25-2.5 mL every 4-6 hours, not to exceed 6 mL/24 hours

Weight 30 lb: 1.25-2.5 mL every 4-6 hours, not to exceed 7 mL/24 hours

Weight 35 lb: 1.25-2.5 mL every 4-6 hours, not to exceed 8 mL/24 hours

Weight 40 lb: 1.25-2.5 mL every 4-6 hours, not to exceed 9 mL/24 hours

6 to <12 years: 2.5-5 mL every 4-6 hours, not to exceed 15 mL/24 hours

Adults: 5 mL every 4-6 hours, not to exceed 30 mL/24 hours

May be administered with food or water to decrease GI upset; avoid alcohol; increase fiber intake and riboflavin in diet

Phenylephrine: Use with caution since phenylephrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response

Promethazine: No information available to require special precautions

Phenylephrine: Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution

Although promethazine is a phenothiazine derivative, extrapyramidal reactions or tardive dyskinesias are not seen with the use of this drug.

See individual agents. Pregnancy/breast-feeding precautions: Inform prescriber if you are or intend to get pregnant. Breast-feeding is not recommended.

Liquid: Promethazine hydrochloride 6.25 mg, phenylephrine hydrochloride 5 mg, and codeine phosphate 10 mg per 5 mL with alcohol 7% (120 mL, 240 mL, 480 mL, 4000 mL)