Interactions with Goldenseal

Goldenseal extract inhibited the cytochrome P450 enzyme system in vitro (Budzinski et al. 2000). Specific interactions between this herb and conventional medications metabolized via the P450 system have not been documented to date. The National Center for Complementary and Alternative Medicine (NCCAM) is funding research to further evaluate interactions between botanicals and drugs (Council for Responsible Nutrition 2000).

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