| |
|
| Glyburide
In a single blind clinical trial of patients with diabetes mellitus, aloe
vera juice (1 tbsp 80% juice bid) combined with glyburide (10 mg glibenclamide)
significantly improved blood sugar levels and decreased triglyceride levels
(Bunyapraphatsara et al. 1996). Glyburide alone was ineffective. The effects of
the combined treatment were not greater than results obtained from treatment
with aloe vera juice alone. Blood glucose levels should be monitored carefully
in diabetic patients using aloe vera either alone or in combination with other
antidiabetic medications in order to avoid potential hypoglycemic
complications. Hydrocortisone
The topical and systemic applications of aloe vera combined with
hydrocortisone 21-acetate significantly reduced edema in mice and rats with
acute inflammation (Davis et al. 1991). Topically, aloe vera (5%) and
hydrocortisone (0.5% aqueous solution) decreased ear inflammation in mice by
85.6%. Systemically, aloe (25 mg/kg and 100 mg/kg) combined with hydrocortisone
(0.1 mg/kg and 100 mg/kg) decreased inflammation in rats by 65.7% compared to
results obtained from either treatment alone; these solutions were injected on a
10 mg/kg basis to measure the inhibitory effects on paw
edema. |
|
|
| References |
|
|
Bunyapraphatsara N, Yongchaiyudha S, Rungpitarangsi V, et al. Antidiabetic
activity of Aloe vera L. juice. II. Clinical trial in diabetes mellitus
patients in combination with glibenclamide. Phytomed. 1996;3:245-248.
Davis RH, Parker WL, Murdoch DP.Aloe vera as a biologically
active vehicle for hydrocortisone acetate. J Am Podiatr Med Assoc.
1991;81:1-9. |
|
|
Copyright © 2000 Integrative Medicine
Communications This publication contains
information relating to general principles
of medical care that should not in any event be construed as specific
instructions for individual patients. The publisher does not accept any
responsibility for the accuracy of the information or the consequences arising
from the application, use, or misuse of any of the information contained herein,
including any injury and/or damage to any person or property as a matter of
product liability, negligence, or otherwise. No warranty, expressed or implied,
is made in regard to the contents of this material. No claims or endorsements
are made for any drugs or compounds currently marketed or in investigative use.
The reader is advised to check product information (including package inserts)
for changes and new information regarding dosage, precautions, warnings,
interactions, and contraindications before administering any drug, herb, or
supplement discussed herein. | |
