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Pronunciation |
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(proe
METH a zeen & deks troe meth
OR fan) |
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U.S. Brand
Names |
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Phenameth® DM; Phenergan® With
Dextromethorphan; Pherazine®
w/DM |
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Generic
Available |
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Yes |
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Synonyms |
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Dextromethorphan and Promethazine |
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Pharmacological Index |
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Antihistamine/Antitussive |
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Use |
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Temporary relief of coughs and upper respiratory symptoms associated with
allergy or the common cold |
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Pregnancy Risk
Factor |
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C |
|
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Warnings/Precautions |
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Research on chicken embryos exposed to concentrations of dextromethorphan
relative to those typically taken by humans has shown to cause birth defects and
fetal death; more study is needed, but it is suggested that pregnant women
should be advised not to use dextromethorphan-containing
medications |
|
|
Usual Dosage |
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Oral:
2-6 years: 1.25-2.5 mL every 4-6 hours up to 10 mL in 24 hours
6-12 years: 2.5-5 mL every 4-6 hours up to 20 mL in 24 hours
Adults: 5 mL every 4-6 hours up to 30 mL in 24 hours |
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|
Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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No information available to require special precautions |
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Dental Health:
Effects on Dental Treatment |
|
Although promethazine is a phenothiazine derivative, extrapyramidal reactions
or tardive dyskinesias are not seen with the use of this
drug. |
|
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Patient
Information |
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See individual agents. Pregnancy/breast-feeding precautions: Inform
prescriber if you are or intend to get pregnant. Breast-feeding is not
recommended. |
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Dosage Forms |
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Syrup: Promethazine hydrochloride 6.25 mg and dextromethorphan hydrobromide
15 mg per 5 mL with alcohol 7% (120 mL, 480 mL, 4000
mL) |
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