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Pronunciation |
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(proe
METH a zeen & KOE
deen) |
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U.S. Brand
Names |
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Phenergan® With Codeine;
Pherazine® With Codeine; Prothazine-DC® |
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Generic
Available |
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Yes |
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Synonyms |
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Codeine and Promethazine |
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Pharmacological Index |
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Antihistamine/Antitussive |
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Use |
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Temporary relief of coughs and upper respiratory symptoms associated with
allergy or the common cold |
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Restrictions |
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C-V |
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Pregnancy Risk
Factor |
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C |
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Usual Dosage |
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Oral (in terms of codeine):
2-6 years: 1.25-2.5 mL every 4-6 hours or 2.5-5 mg/dose every 4-6 hours as
needed; maximum: 30 mg codeine/day
6-12 years: 2.5-5 mL every 4-6 hours as needed or 5-10 mg/dose every 4-6
hours as needed; maximum: 60 mg codeine/day
Adults: 10-20 mg/dose every 4-6 hours as needed; maximum: 120 mg codeine/day;
or 5-10 mL every 4-6 hours as needed |
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Dietary
Considerations |
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Increase fluids, fiber intake, and riboflavin in diet |
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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No information available to require special precautions |
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Dental Health:
Effects on Dental Treatment |
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Although promethazine is a phenothiazine derivative, extrapyramidal reactions
or tardive dyskinesias are not seen with the use of this
drug. |
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Patient
Information |
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See individual agents. Pregnancy/breast-feeding precautions: Inform
prescriber if you are or intend to get pregnant. Breast-feeding is not
recommended. |
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Nursing
Implications |
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May cause sedation and drowsiness |
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Dosage Forms |
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Syrup: Promethazine hydrochloride 6.25 mg and codeine phosphate 10 mg per 5
mL (120 mL, 180 mL, 473 mL) |
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