Hydrocodone, Phenylephrine, Pyrilamine, Phenindamine, Chlorpheniramine, and Ammonium Chloride

Interactions with herbs

Hawthorn

Interactions with supplements

Creatine

Look Up > Drugs > Hydrocodone, Phenylephrine, Pyrilamine, Phenindamine, Chlorpheniramine, and Ammonium Chloride

Hydrocodone, Phenylephrine, Pyrilamine, Phenindamine, Chlorpheniramine, and Ammonium Chloride

	Pronunciation
	U.S. Brand Names
	Generic Available
	Pharmacological Index
	Use
	Usual Dosage
	Dental Health: Local Anesthetic/Vasoconstrictor Precautions
	Dental Health: Effects on Dental Treatment
	Dosage Forms

Pronunciation

(hye droe KOE done, fen il EF rin, peer IL a meen, fen IN da meen, klor fen IR a meen, & a MOE nee um KLOR ide)

U.S. Brand Names

P-V-Tussin®

Generic Available

Yes

Pharmacological Index

Antihistamine/Decongestant/Antitussive

Use

Symptomatic relief of cough and nasal congestion

Usual Dosage

Adults: Oral: 10 mL every 4-6 hours, up to 40 mL/day

Dental Health: Local Anesthetic/Vasoconstrictor Precautions

Use with caution since phenylephrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response

Dental Health: Effects on Dental Treatment

Chlorpheniramine: Prolonged use will cause significant xerostomia

Phenylephrine: Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution

Dosage Forms

Syrup: Hydrocodone bitartrate 2.5 mg, phenylephrine hydrochloride 5 mg, pyrilamine maleate 6 mg, phenindamine tartrate 5 mg, chlorpheniramine maleate 2 mg, and ammonium chloride 50 mg per 5 mL with alcohol 5% (480 mL, 3780 mL)