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Pronunciation |
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(gwye
FEN e sin & fen il EF
rin) |
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U.S. Brand
Names |
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Deconsal®
Sprinkle®; Endal®; Sinupan® |
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Generic
Available |
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No |
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Synonyms |
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Phenylephrine and Guaifenesin |
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Pharmacological Index |
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Decongestant; Expectorant |
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Use |
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Symptomatic relief of those respiratory conditions where tenacious mucous
plugs and congestion complicate the problem such as sinusitis, pharyngitis,
bronchitis, asthma, and as an adjunctive therapy in serous otitis
media |
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Adverse
Reactions |
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See individual agents |
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Drug
Interactions |
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See individual agents |
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Mechanism of
Action |
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See individual agents |
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Usual Dosage |
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Oral: Adults: 1 or 2 every 12 hours |
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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Use with caution since phenylephrine is a sympathomimetic amine which could
interact with epinephrine to cause a pressor response |
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Dental Health:
Effects on Dental Treatment |
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Guaifenesin: No effects or complications reported
Phenylephrine: Up to 10% of patients could experience tachycardia,
palpitations, and dry mouth; use vasoconstrictor with caution
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Dosage Forms |
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Capsule, sustained release:
Deconsal® Sprinkle®: Guaifenesin
300 mg and phenylephrine hydrochloride 10 mg
Sinupan®: Guaifenesin 200 mg and phenylephrine
hydrochloride 40 mg
Tablet, timed release (Endal®): Guaifenesin 300 mg and
phenylephrine hydrochloride 20 mg |
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