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Look Up > Drugs > Guaifenesin and Phenylephrine
Guaifenesin and Phenylephrine
Pronunciation
U.S. Brand Names
Generic Available
Synonyms
Pharmacological Index
Use
Adverse Reactions
Drug Interactions
Mechanism of Action
Usual Dosage
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Dosage Forms

Pronunciation
(gwye FEN e sin & fen il EF rin)

U.S. Brand Names
Deconsal® Sprinkle®; Endal®; Sinupan®

Generic Available

No


Synonyms
Phenylephrine and Guaifenesin

Pharmacological Index

Decongestant; Expectorant


Use

Symptomatic relief of those respiratory conditions where tenacious mucous plugs and congestion complicate the problem such as sinusitis, pharyngitis, bronchitis, asthma, and as an adjunctive therapy in serous otitis media


Adverse Reactions

See individual agents


Drug Interactions

See individual agents


Mechanism of Action

See individual agents


Usual Dosage

Oral: Adults: 1 or 2 every 12 hours


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

Use with caution since phenylephrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response


Dental Health: Effects on Dental Treatment

Guaifenesin: No effects or complications reported

Phenylephrine: Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution


Dosage Forms

Capsule, sustained release:

Deconsal® Sprinkle®: Guaifenesin 300 mg and phenylephrine hydrochloride 10 mg

Sinupan®: Guaifenesin 200 mg and phenylephrine hydrochloride 40 mg

Tablet, timed release (Endal®): Guaifenesin 300 mg and phenylephrine hydrochloride 20 mg


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