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Pronunciation |
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(gwye
FEN e sin, fen il proe pa NOLE a
meen, & fen il EF rin) |
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U.S. Brand
Names |
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Coldloc®; Contuss®;
Dura-Gest®; Enomine®; Entex®; Guaifenex®;
Guiatex® |
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Generic
Available |
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Yes |
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Synonyms |
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Phenylephrine, Guaifenesin, and Phenylpropanolamine; Phenylpropanolamine,
Guaifenesin, and Phenylephrine |
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Pharmacological Index |
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Decongestant; Expectorant |
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Use |
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Temporary relief of nasal congestion, running nose, sneezing, itching of nose
and throat, and itchy, watery eyes due to common cold, hay fever, or other upper
respiratory allergies |
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Pregnancy Risk
Factor |
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C |
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Usual Dosage |
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Children >12 years and Adults: 1 capsule/tablet or 10 mL 4 times/day
(every 6 hours) with food or fluid |
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Dietary
Considerations |
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Administer with food or fluid |
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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Use with caution since phenylpropanolamine and phenylephrine are
sympathomimetic amines which could interact with epinephrine to cause a pressor
response |
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Dental Health:
Effects on Dental Treatment |
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Guaifenesin: No effects or complications reported
Phenylephrine, Phenylpropanolamine: Up to 10% of patients could experience
tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution
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Patient
Information |
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See individual agents. Pregnancy/breast-feeding precautions: Inform
prescriber if you are or intend to get pregnant. Consult prescriber if
breast-feeding. |
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Nursing
Implications |
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Extended release tablets may be cut in half and still maintain effective
release properties, do not crush or chew |
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Dosage Forms |
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Capsule (Contuss®, Dura-Gest®,
Enomine®, Entex®,
Guiatex®, ULR®): Guaifenesin 200 mg,
phenylpropanolamine hydrochloride 45 mg, and phenylephrine hydrochloride 5 mg
Liquid (Coldloc®, Contuss®,
Entex®, Guaifenex®): Guaifenesin 100
mg, phenylpropanolamine hydrochloride 20 mg, and phenylephrine hydrochloride 5
mg per 5 mL (118 mL, 480 mL)
Tablet (Respinol-G®): Guaifenesin 200 mg,
phenylpropanolamine hydrochloride 45 mg, and phenylephrine hydrochloride 5 mg
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