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Pronunciation |
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(gwye
FEN e sin, fen il proe pa NOLE a
meen, & deks troe meth OR fan) |
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U.S. Brand
Names |
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Anatuss®[OTC]; Guiatuss CF®[OTC];
Naldecon® DX Adult Liquid [OTC]; Profen II DM®;
Robafen® CF [OTC]; Robitussin-CF®[OTC];
Siltussin-CF®[OTC] |
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Generic
Available |
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Yes |
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Synonyms |
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Dextromethorphan, Guaifenesin, and Phenylpropanolamine; Phenylpropanolamine,
Guaifenesin, and Dextromethorphan |
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Pharmacological Index |
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Cough Preparation; Decongestant; Expectorant |
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Use |
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Temporarily relieves nasal congestion and controls cough due to minor throat
and bronchial irritation; helps loosen phlegm and thin bronchial secretions to
make coughs more productive |
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Pregnancy Risk
Factor |
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C |
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Warnings/Precautions |
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Research on chicken embryos exposed to concentrations of dextromethorphan
relative to those typically taken by humans has shown to cause birth defects and
fetal death; more study is needed, but it is suggested that pregnant women
should be advised not to use dextromethorphan-containing
medications |
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Usual Dosage |
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Oral:
2-6 years: 2.5 mL every 4 hours not to exceed 15 mL/24 hours
6-12 years: 5 mL every 4 hours not to exceed 30 mL/24 hours
Children >12 years and Adults: 10 mL every 4 hours not to exceed 60 mL/24
hours |
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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Use with caution since phenylpropanolamine is a sympathomimetic amine which
could interact with epinephrine to cause a pressor response |
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Dental Health:
Effects on Dental Treatment |
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Dextromethorphan, Guaifenesin: No effects or complications reported
Phenylpropanolamine: Up to 10% of patients could experience tachycardia,
palpitations, and dry mouth; use vasoconstrictor with caution
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Patient
Information |
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See individual agents. Pregnancy/breast-feeding precautions: Inform
prescriber if you are or intend to get pregnant. Breast-feeding is not
recommended. |
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Dosage Forms |
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Syrup:
Anatuss®: Guaifenesin 100 mg, phenylpropanolamine
hydrochloride 25 mg, and dextromethorphan hydrobromide 15 mg per 5 mL (120 mL,
473 mL)
Guiatuss® CF, Robafen® CF,
Robitussin-CF®: Guaifenesin 100 mg, phenylpropanolamine
hydrochloride 12.5 mg, and dextromethorphan hydrobromide 10 mg per 5 mL (120 mL,
240 mL, 360 mL, 480 mL)
Naldecon® DX Adult: Guaifenesin 200 mg,
phenylpropanolamine hydrochloride 12.5 mg, and dextromethorphan hydrobromide 10
mg per 5 mL (120 mL, 473 mL)
Siltussin-CF®: Guaifenesin 100 mg, phenylpropanolamine
hydrochloride 12.5 mg, and dextromethorphan hydrobromide 10 mg per 5 mL
Tablet: (Anatuss®): Guaifenesin 100 mg,
phenylpropanolamine hydrochloride 25 mg, and dextromethorphan hydrobromide 15 mg
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