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Pronunciation |
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(ep
i NEF rin, ra SEE mik and a LOO mi
num poe TASS ee um SUL fate) |
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U.S. Brand
Names |
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Van R
Gingibraid® |
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Generic
Available |
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No |
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Pharmacological Index |
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Adrenergic Agonist Agent; Alpha/Beta Agonist; Astringent;
Vasoconstrictor |
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Use |
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Dental: Gingival retraction
Medical: None |
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Contraindications |
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Patients with cardiovascular disease, hyperthyroidism, or diabetes; patients
sensitive to epinephrine; do not apply to areas of heavy or deep bleeding or
over exposed bone |
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Warnings/Precautions |
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Caution should be exercised whenever using gingival retraction cords with
epinephrine since it delivers vasoconstrictor doses of racemic epinephrine to
patients; the general medical history should be thoroughly evaluated before
using in any patient |
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Adverse
Reactions |
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No data reported |
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Drug
Interactions |
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No data reported |
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Mechanism of
Action |
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Epinephrine stimulates alpha1 adrenergic receptors to cause
vasoconstriction in blood vessels in gingiva; aluminum potassium sulfate,
precipitates tissue and blood proteins |
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Pharmacodynamics/Kinetics |
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No data reported |
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Usual Dosage |
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Pass the impregnated yarn around the neck of the tooth and place into
gingival sulcus; normal tissue moisture, water, or gingival retraction solutions
activate impregnated yarn. Limit use to one quadrant of the mouth at a time;
recommended use is for 3-8 minutes in the mouth. |
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Dietary
Considerations |
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No data reported |
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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No information available to require special precautions |
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Dental Health:
Effects on Dental Treatment |
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Tissue retraction around base of the tooth (therapeutic
effect) |
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Dosage Forms |
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Yarn, saturated in solution of 8% racemic epinephrine and 7% aluminum
potassium sulfate; yarn labeled type "0e" contains
0.20±0.10 mg epinephrine per inch; "1e" contains
0.40±0.20 mg per inch; "2e" contains
0.60±0.20 mg per inch |
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