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Pronunciation |
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(klor
fen IR a meen & fen il EF
rin) |
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U.S. Brand
Names |
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Dallergy-D® Syrup; Ed A-Hist®
Liquid; Histatab® Plus Tablet [OTC]; Histor-D® Syrup;
Rolatuss® Plain Liquid; Ru-Tuss®
Liquid |
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Generic
Available |
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Yes |
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Synonyms |
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Phenylephrine and Chlorpheniramine |
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Pharmacological Index |
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Antihistamine/Decongestant Combination |
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Use |
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Temporary relief of nasal congestion and eustachian tube congestion as well
as runny nose, sneezing, itching of nose or throat, itchy and watery
eyes |
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Pregnancy Risk
Factor |
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C |
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Usual Dosage |
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Oral:
2-5 years: 2.5 mL every 4 hours
6-12 years: 5 mL every 4 hours
Adults: 10 mL every 4 hours |
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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Use with caution since phenylephrine is a sympathomimetic amine which could
interact with epinephrine to cause a pressor response |
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Dental Health:
Effects on Dental Treatment |
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Chlorpheniramine: Prolonged use will cause significant xerostomia
Phenylephrine: Up to 10% of patients could experience tachycardia,
palpitations, and dry mouth; use vasoconstrictor with caution; prolonged use
will cause significant xerostomia |
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Patient
Information |
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May cause drowsiness. Avoid driving or operating machinery while taking this
medication. |
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Dosage Forms |
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Capsule, sustained release: Chlorpheniramine maleate 8 mg and phenylephrine
hydrochloride 20 mg
Liquid:
Dallergy-D®, Histor-D®,
Rolatuss® Plain, Ru-Tuss®:
Chlorpheniramine maleate 2 mg and phenylephrine hydrochloride 5 mg per 5 mL
Ed A-Hist® Liquid: Chlorpheniramine maleate 4 mg and
phenylephrine hydrochloride 10 mg per 5 mL
Tablet (Histatab® Plus): Chlorpheniramine maleate 2 mg
and phenylephrine hydrochloride 5 mg |
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