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Hawthorn
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Look Up > Drugs > Chlorpheniramine and Phenylephrine
Chlorpheniramine and Phenylephrine
Pronunciation
U.S. Brand Names
Generic Available
Synonyms
Pharmacological Index
Use
Pregnancy Risk Factor
Usual Dosage
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Dosage Forms

Pronunciation
(klor fen IR a meen & fen il EF rin)

U.S. Brand Names
Dallergy-D® Syrup; Ed A-Hist® Liquid; Histatab® Plus Tablet [OTC]; Histor-D® Syrup; Rolatuss® Plain Liquid; Ru-Tuss® Liquid

Generic Available

Yes


Synonyms
Phenylephrine and Chlorpheniramine

Pharmacological Index

Antihistamine/Decongestant Combination


Use

Temporary relief of nasal congestion and eustachian tube congestion as well as runny nose, sneezing, itching of nose or throat, itchy and watery eyes


Pregnancy Risk Factor

C


Usual Dosage

Oral:

2-5 years: 2.5 mL every 4 hours

6-12 years: 5 mL every 4 hours

Adults: 10 mL every 4 hours


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

Use with caution since phenylephrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response


Dental Health: Effects on Dental Treatment

Chlorpheniramine: Prolonged use will cause significant xerostomia

Phenylephrine: Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution; prolonged use will cause significant xerostomia


Patient Information

May cause drowsiness. Avoid driving or operating machinery while taking this medication.


Dosage Forms

Capsule, sustained release: Chlorpheniramine maleate 8 mg and phenylephrine hydrochloride 20 mg

Liquid:

Dallergy-D®, Histor-D®, Rolatuss® Plain, Ru-Tuss®: Chlorpheniramine maleate 2 mg and phenylephrine hydrochloride 5 mg per 5 mL

Ed A-Hist® Liquid: Chlorpheniramine maleate 4 mg and phenylephrine hydrochloride 10 mg per 5 mL

Tablet (Histatab® Plus): Chlorpheniramine maleate 2 mg and phenylephrine hydrochloride 5 mg


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