Chlorpheniramine, Phenylephrine, and Methscopolamine

Interactions with herbs

Hawthorn

Interactions with supplements

Creatine

Look Up > Drugs > Chlorpheniramine, Phenylephrine, and Methscopolamine

Chlorpheniramine, Phenylephrine, and Methscopolamine

	Pronunciation
	U.S. Brand Names
	Generic Available
	Pharmacological Index
	Use
	Usual Dosage
	Dental Health: Local Anesthetic/Vasoconstrictor Precautions
	Dental Health: Effects on Dental Treatment
	Dosage Forms

Pronunciation

(klor fen IR a meen, fen il EF rin, & meth skoe POL a meen)

U.S. Brand Names

D.A.II® Tablet; Dallergy®; Dura-Vent/DA®; Extendryl® SR; Histor-D® Timecelles®

Generic Available

Yes

Pharmacological Index

Antihistamine/Decongestant/Anticholinergic

Use

Relieves nasal congestion, runny nose and sneezing

Usual Dosage

Adults: Oral: 1 capsule every 12 hours

Dental Health: Local Anesthetic/Vasoconstrictor Precautions

Use with caution since phenylephrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response

Dental Health: Effects on Dental Treatment

Chlorpheniramine: Prolonged use will cause significant xerostomia

Methscopolamine: Anticholinergic side effects can cause a reduction of saliva production or secretion contributes to discomfort and dental disease (ie, caries, oral candidiasis and periodontal disease)

Phenylephrine: Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution

Dosage Forms

Caplet, sustained release: Chlorpheniramine maleate 8 mg, phenylephrine hydrochloride 20 mg, and methscopolamine nitrate 2.5 mg

Capsule, sustained release: Chlorpheniramine maleate 8 mg, phenylephrine hydrochloride 10 mg, and methscopolamine nitrate 2.5 mg

Syrup: Chlorpheniramine maleate 2 mg, phenylephrine hydrochloride 10 mg, and methscopolamine nitrate 0.625 mg per 5 mL

Tablet: Chlorpheniramine maleate 4 mg, phenylephrine hydrochloride 10 mg, and methscopolamine nitrate 1.25 mg