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Look Up > Drugs > Chlorpheniramine, Phenylephrine, and Dextromethorphan
Chlorpheniramine, Phenylephrine, and Dextromethorphan
Pronunciation
U.S. Brand Names
Generic Available
Pharmacological Index
Use
Warnings/Precautions
Usual Dosage
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Dosage Forms

Pronunciation
(klor fen IR a meen, fen il EF rin, & deks troe meth OR fan)

U.S. Brand Names
Cerose-DM®[OTC]

Generic Available

No


Pharmacological Index

Antihistamine/Decongestant/Antitussive


Use

Temporary relief of cough due to minor throat and bronchial irritation; relieves nasal congestion, runny nose and sneezing


Warnings/Precautions

Research on chicken embryos exposed to concentrations of dextromethorphan relative to those typically taken by humans has shown to cause birth defects and fetal death; more study is needed, but it is suggested that pregnant women should be advised not to use dextromethorphan-containing medications


Usual Dosage

Adults: Oral: 5-10 mL 4 times/day


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

Chlorpheniramine, Dextromethorphan: No information available to require special precautions

Phenylephrine: Use with caution since phenylephrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response


Dental Health: Effects on Dental Treatment

Chlorpheniramine: Prolonged use will cause significant xerostomia

Dextromethorphan: No effects or complications reported

Phenylephrine: Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution; prolonged use will cause significant xerostomia


Dosage Forms

Liquid: Chlorpheniramine maleate 4 mg, phenylephrine hydrochloride 10 mg, and dextromethorphan hydrobromide 15 mg per 5 mL


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