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Look Up > Drugs > Brompheniramine and Phenylephrine
Brompheniramine and Phenylephrine
Pronunciation
U.S. Brand Names
Generic Available
Pharmacological Index
Use
Pregnancy Risk Factor
Adverse Reactions
Drug Interactions
Usual Dosage
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Dosage Forms

Pronunciation
(brome fen IR a meen & fen il EF rin)

U.S. Brand Names
Dimetane® Decongestant Elixir [OTC]

Generic Available

Yes


Pharmacological Index

Antihistamine/Decongestant Combination


Use

Temporary relief of symptoms of seasonal and perennial allergic rhinitis, and vasomotor rhinitis, including nasal obstruction


Pregnancy Risk Factor

C


Adverse Reactions

>10%:

Cardiovascular: Tachycardia

Central nervous system: Slight to moderate drowsiness, nervousness, transient stimulation, insomnia

Respiratory: Thickening of bronchial secretions

1% to 10%:

Central nervous system: Headache, fatigue, nervousness, dizziness

Gastrointestinal: Appetite increase, weight increase, nausea, diarrhea, abdominal pain, dry mouth

Genitourinary: Dysuria

Neuromuscular & skeletal: Arthralgia, weakness

Respiratory: Pharyngitis

Miscellaneous: Sweating

<1%:

Cardiovascular: Edema, palpitations, hypotension

Central nervous system: Depression, sedation, paradoxical excitement, convulsions, hallucinations

Dermatologic: Angioedema, rash, photosensitivity

Genitourinary: Urinary retention

Hepatic: Hepatitis

Neuromuscular & skeletal: Myalgia, paresthesia, tremor

Ocular: Blurred vision

Respiratory: Bronchospasm, epistaxis, dyspnea


Drug Interactions

CNS depressants, MAO inhibitors, sympathomimetics, Rauwolfia alkaloids, tricyclic antidepressants, ganglionic blocking agents, propranolol


Usual Dosage

Children >12 years and Adults: Oral: 10 mL every 4 hours


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

Brompheniramine: No information available to require special precautions

Phenylephrine: Use with caution since phenylephrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response


Dental Health: Effects on Dental Treatment

Brompheniramine: Prolonged use may decrease salivary flow

Phenylephrine: Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution


Dosage Forms

Elixir: Brompheniramine maleate 4 mg and phenylephrine hydrochloride 5 mg per 5 mL


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