Changes in Chromosomal Number

Pharmakon

(

Down's Syndrome ( Trisomy #21

- mental retardation
- short stature, round face
- more likely in women over 40
- retardation is now known to be caused the the GART gene

Other Syndromes :-
Turner (XO), Klinefelter (XXY),
Edward (Trisomy 13), Supermale (XYY),
Poly-X Females (XXX)