Iprtropium Bromide

dr.joan

Iprtropium Bromide:
Trade names: Atrovent
Action: Antimuscarinic bronchodilators

Drug classes

· Anticholinergic
· Antimuscarinic agent
· Parasympatholytic
Pregnancy: (Category

Therapeutic actions

· Anticholinergic, chemically related to atropine, which blocks vagally mediated reflexes by antagonizing the action of acetylcholine.

Indications

· Bronchodilator for maintenance treatment of bronchospasm associated with COPD (solution, aerosol)
· Symptomatic relief of rhinorrhea associated with perennial rhinitis, common cold (nasal spray)

Contraindications/cautions

· Contraindications: hypersensitivity to atropine or its derivatives, acute episodes of bronchospasm.
· Use cautiously with narrow-angle glaucoma, prostatic hypertrophy, bladder neck obstruction, pregnancy, lactation.
Dose:
§ By inhalation of nebulised solution, 100–500 micrograms up to 4 times daily;
§ CHILD 1 month–3 years 62.5–250 micrograms up to 3 times daily [unlicensed];
§ 3–14 years 100–500 micrograms up to 3 times daily.
Adverse effects
§ CNS: Nervousness, dizziness, headache, fatigue, insomnia, blurred vision
§ GI: Nausea, GI distress, dry mouth
§ Respiratory: Cough, exacerbation of symptoms, hoarseness
§ Other: Palpitations, rash


Nursing Considerations
§ Protect solution for inhalation from light. Store unused vials in foil pouch.
§ Ensure adequate hydration; provide environmental control (temperature) to prevent hyperpyrexia.
§ Have patient void before taking medication to avoid urinary retention.
§ Teach patient proper use of inhalator.