Wild Yam
  Uses of this Herb
Gallbladder Disease
Infantile Colic
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Western Herbalism
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Interactions with Wild Yam

Dietary provisions of diosgenin (1% w/w) for 6 days reduced the cholestatic effects of estradiol-17b-(b-D-glucuronide) (1.1 mmol/100g IV) in rats (Accatino et al. 1998). In addition, the diosgenin-supplemented diet prevented some of the cholestatic effects of 17 a-ethynylestradiol (5 mg/kg subcutaneously), such as increased biliary alkaline phosphatase and decreased taurocholate SRm.


Accatino L, Pizarro M, Solis N, Koenig C. Effects of diosgenin, a plant derived steroid, on bile secretion and hepatocellular cholestasis induced by estrogens in the rat. Hepatol. 1998;28(1):129-140.

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