with Wild Yam|
Dietary provisions of diosgenin (1% w/w) for 6 days reduced the cholestatic
(1.1 mmol/100g IV) in rats (Accatino et al. 1998). In
addition, the diosgenin-supplemented diet prevented some of the cholestatic
effects of 17 a-ethynylestradiol (5 mg/kg
subcutaneously), such as increased biliary alkaline phosphatase and decreased
Accatino L, Pizarro M, Solis N, Koenig C. Effects of diosgenin, a plant
derived steroid, on bile secretion and hepatocellular cholestasis induced by
estrogens in the rat. Hepatol.
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