No specific interactions between feverfew and conventional medications have
been adequately researched to draw conclusions. However, a potential interaction
with non-steroidal anti-inflammatory drugs (NSAIDs) has been raised, because of
prostaglandin inhibition by NSAIDs, which may reduce the effectiveness of
feverfew (Miller 1998). Additionally, because of the platelet inhibitory effects
of feverfew, patients taking anticoagulants with feverfew should be monitored
closely for clinical signs of bleeding abnormalities.
Miller LG. Herbal medicinals: selected clinical considerations focusing on
known or potential drug-herb interactions. Arch Intern Med.
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