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Triamcinolone Acetonide Paste (Dental)
Pronunciation
U.S. Brand Names
Generic Available
Pharmacological Index
Use
Pregnancy Risk Factor
Contraindications
Warnings/Precautions
Adverse Reactions
Drug Interactions
Mechanism of Action
Pharmacodynamics/Kinetics
Usual Dosage
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Dosage Forms

Pronunciation
(trye am SIN oh lone a SEE toe nide DEN tal paste)

U.S. Brand Names
Kenalog® in Orabase®

Generic Available

Yes


Pharmacological Index

Anti-inflammatory Agent; Corticosteroid, Topical


Use

Dental: For adjunctive treatment and for the temporary relief of symptoms associated with oral inflammatory lesions and ulcerative lesions resulting from trauma

Medical: Localized inflammation responsive to steroids


Pregnancy Risk Factor

C


Contraindications

Known hypersensitivity to triamcinolone; contraindicated in the presence of fungal, viral, or bacterial infections of the mouth or throat


Warnings/Precautions

Patients with tuberculosis, peptic ulcer or diabetes mellitus should not be treated with any corticosteroid preparation without the advice of the patient's physician. Normal immune responses of the oral tissues are depressed in patients receiving topical corticosteroid therapy. Virulent strains of oral microorganisms may multiply without producing the usual warning symptoms of oral infections. The small amount of steroid released from the topical preparation makes systemic effects very unlikely. If local irritation or sensitization should develop, the preparation should be discontinued. If significant regeneration or repair of oral tissues has not occurred in seven days, re-evaluation of the etiology of the oral lesion is advised.


Adverse Reactions

No data reported


Drug Interactions

No data reported


Mechanism of Action

Decreases inflammation by suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability; suppresses the immune system by reducing activity and volume of the lymphatic system; suppresses adrenal function at high doses


Pharmacodynamics/Kinetics

Absorption: Topical: Systemic absorption may occur

Serum half-life: Biological: 18-36 hours


Usual Dosage

Press a small dab (about 1/4 inch) to the lesion until a thin film develops. A larger quantity may be required for coverage of some lesions. For optimal results use only enough to coat the lesion with a thin film.


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Dosage Forms

Tubes: 5 g; each g provides 1 mg (0.1%) triamcinolone in emollient dental paste containing gelatin, pectin, and carboxymethylcellulose sodium in a polyethylene and mineral oil gel base


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