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Pronunciation |
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(trye
am SIN oh lone a SEE toe nide
DEN tal paste) |
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U.S. Brand
Names |
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Kenalog® in
Orabase® |
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Generic
Available |
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Yes |
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Pharmacological Index |
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Anti-inflammatory Agent; Corticosteroid, Topical |
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Use |
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Dental: For adjunctive treatment and for the temporary relief of symptoms
associated with oral inflammatory lesions and ulcerative lesions resulting from
trauma
Medical: Localized inflammation responsive to steroids |
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Pregnancy Risk
Factor |
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C |
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Contraindications |
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Known hypersensitivity to triamcinolone; contraindicated in the presence of
fungal, viral, or bacterial infections of the mouth or
throat |
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Warnings/Precautions |
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Patients with tuberculosis, peptic ulcer or diabetes mellitus should not be
treated with any corticosteroid preparation without the advice of the patient's
physician. Normal immune responses of the oral tissues are depressed in patients
receiving topical corticosteroid therapy. Virulent strains of oral
microorganisms may multiply without producing the usual warning symptoms of oral
infections. The small amount of steroid released from the topical preparation
makes systemic effects very unlikely. If local irritation or sensitization
should develop, the preparation should be discontinued. If significant
regeneration or repair of oral tissues has not occurred in seven days,
re-evaluation of the etiology of the oral lesion is
advised. |
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Adverse
Reactions |
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No data reported |
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Drug
Interactions |
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No data reported |
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Mechanism of
Action |
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Decreases inflammation by suppression of migration of polymorphonuclear
leukocytes and reversal of increased capillary permeability; suppresses the
immune system by reducing activity and volume of the lymphatic system;
suppresses adrenal function at high doses |
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Pharmacodynamics/Kinetics |
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Absorption: Topical: Systemic absorption may occur
Serum half-life: Biological: 18-36 hours |
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Usual Dosage |
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Press a small dab (about
1/4
inch) to the lesion until a thin film develops. A larger quantity may be
required for coverage of some lesions. For optimal results use only enough to
coat the lesion with a thin film. |
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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No information available to require special precautions |
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Dental Health:
Effects on Dental Treatment |
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No effects or complications reported |
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Dosage Forms |
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Tubes: 5 g; each g provides 1 mg (0.1%) triamcinolone in emollient dental
paste containing gelatin, pectin, and carboxymethylcellulose sodium in a
polyethylene and mineral oil gel
base |
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