| Pronunciation |
 (tole
NAF
tate) |
 |
| U.S. Brand Names |
| Absorbine® Antifungal [OTC]; Absorbine® Jock Itch [OTC]; Absorbine Jr.® Antifungal [OTC]; Aftate® for Athlete's Foot [OTC]; Aftate® for Jock Itch [OTC]; Blis-To-Sol®[OTC]; Breezee® Mist Antifungal [OTC]; Dr Scholl's Athlete's Foot [OTC]; Dr Scholl's Maximum Strength Tritin [OTC]; Genaspor®[OTC]; NP-27®[OTC]; Quinsana Plus®[OTC]; Tinactin®[OTC]; Tinactin® for Jock Itch [OTC]; Ting®[OTC] |
|
| Generic Available |
|
Yes |
|
| Pharmacological Index |
|
Antifungal Agent, Topical |
|
| Use |
|
Treatment of tinea pedis, tinea cruris, tinea corporis, tinea manuum, tinea versicolor infections |
|
| Pregnancy Risk Factor |
|
C |
|
| Contraindications |
|
Known hypersensitivity to tolnaftate; nail and scalp infections |
|
| Warnings/Precautions |
|
Cream is not recommended for nail or scalp infections; keep from eyes; if no improvement within 4 weeks, treatment should be discontinued. Usually not effective alone for the treatment of infections involving hair follicles or nails. |
|
| Adverse Reactions |
|
1% to 10%: Local: Irritation, stinging |
|
| Drug Interactions |
|
No data reported |
|
| Mechanism of Action |
|
Distorts the hyphae and stunts mycelial growth in susceptible fungi |
|
| Pharmacodynamics/Kinetics |
|
Onset of action: 24-72 hours |
|
| Usual Dosage |
|
Children and Adults: Topical: Wash and dry affected area; apply 1-3 drops of solution or a small amount of cream or powder and rub into the affected areas 2-3 times/day for 2-4 weeks |
|
| Mental Health: Effects on Mental Status |
|
None noted |
|
| Mental Health: Effects on Psychiatric Treatment |
|
None noted |
|
| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
|
| Dental Health: Effects on Dental Treatment |
|
No effects or complications reported |
|
| Patient Information |
|
Avoid contact with the eyes; apply to clean dry area; consult the physician if a skin irritation develops or if the skin infection worsens or does not improve after 10 days of therapy; does not stain skin or clothing |
|
| Nursing Implications |
|
Itching, burning, and soreness are usually relieved within 24-72 hours |
|
| Dosage Forms |
|
Aerosol, topical: Liquid: 1% (59.2 mL, 90 mL, 120 mL) Powder: 1% (56.7 g, 100 g, 105 g, 150 g) Cream: 1% (15 g, 30 g) Gel, topical: 1% (15 g) Powder, topical: 1% (45 g, 90 g) Solution, topical: 1% (10 mL) |
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