| Pronunciation |
 (tye
oh PROE
nin) |
 |
| U.S. Brand Names |
| Thiola™ |
|
| Generic Available |
|
No |
|
| Pharmacological Index |
|
Urinary Tract Product |
|
| Use |
|
Prevention of kidney stone (cystine) formation in patients with severe homozygous cystinuric who have urinary cystine >500 mg/day who are resistant to treatment with high fluid intake, alkali, and diet modification, or who have had adverse reactions to penicillamine |
|
| Pregnancy Risk Factor |
|
C |
|
| Usual Dosage |
|
Adults: Initial dose is 800 mg/day, average dose is 1000 mg/day |
|
| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
|
| Dental Health: Effects on Dental Treatment |
|
No effects or complications reported |
|
| Patient Information |
|
Take on an empty stomach (1 hour before or 2 hours after meals) with a full glass of water. Maintain adequate hydration (2-3 L/day). You may experience night voiding (normal); nausea or vomiting (frequent small meals, frequent mouth care, or sucking on lozenges may help); or diarrhea (buttermilk or yogurt may help). Report promptly any unusual bruising or bleeding fatigue, abdominal pain, or acute headache, yellowing of skin or eyes, swelling of extremities, increased weight (>5 lb/week), respiratory difficulty, pain on urination, or cloudy or bloody urine. Inform prescriber if you are pregnant. Do not breast-feed. |
|
| Dosage Forms |
|
Tablet: 100 mg |
|
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