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Sulconazole
Pronunciation
U.S. Brand Names
Generic Available
Synonyms
Pharmacological Index
Use
Pregnancy Risk Factor
Contraindications
Warnings/Precautions
Adverse Reactions
Drug Interactions
Mechanism of Action
Pharmacodynamics/Kinetics
Usual Dosage
Mental Health: Effects on Mental Status
Mental Health: Effects on Psychiatric Treatment
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Nursing Implications
Dosage Forms

Pronunciation
(sul KON a zole)

U.S. Brand Names
Exelderm® Topical

Generic Available

No


Synonyms
Sulconazole Nitrate

Pharmacological Index

Antifungal Agent, Topical


Use

Treatment of superficial fungal infections of the skin, including tinea cruris (jock itch), tinea corporis (ringworm), tinea versicolor, and possibly tinea pedis (athlete's foot - cream only)


Pregnancy Risk Factor

C


Contraindications

Known hypersensitivity to sulconazole


Warnings/Precautions

Use with caution in nursing mothers; for external use only


Adverse Reactions

1% to 10%:

Local: Burning, stinging, redness


Drug Interactions

No data reported


Mechanism of Action

Substituted imidazole derivative which inhibits metabolic reactions necessary for the synthesis of ergosterol, an essential membrane component. The end result is usually fungistatic; however, sulconazole may act as a fungicide in Candida albicans and parapsilosis during certain growth phases.


Pharmacodynamics/Kinetics

Absorption: Topical: About 8.7% absorbed percutaneously

Elimination: Mostly in urine


Usual Dosage

Adults: Topical: Apply a small amount to the affected area and gently massage once or twice daily for 3 weeks (tinea cruris, tinea corporis, tinea versicolor) to 4 weeks (tinea pedis).


Mental Health: Effects on Mental Status

None reported


Mental Health: Effects on Psychiatric Treatment

None reported


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Patient Information

For external use only; avoid contact with eyes; if burning or irritation develops, notify physician


Nursing Implications

For external use only; avoid contact with eyes; if burning or irritation develops, notify physician


Dosage Forms

Cream, as nitrate: 1% (15 g, 30 g, 60 g)

Solution, as nitrate, topical: 1% (30 mL)


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