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Pronunciation |
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(SOW
dee um tetra DEK
il) |
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U.S. Brand
Names |
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Sotradecol®
Injection |
|
|
Generic
Available |
|
No |
|
|
Synonyms |
|
Sodium Tetradecyl Sulfate |
|
|
Pharmacological Index |
|
Sclerosing Agent |
|
|
Use |
|
Treatment of small, uncomplicated varicose veins of the lower extremities;
endoscopic sclerotherapy in the management of bleeding esophageal
varices |
|
|
Pregnancy Risk
Factor |
|
C |
|
|
Contraindications |
|
Arterial disease, thrombophlebitis, hypersensitivity to sodium tetradecyl or
any component, valvular or deep vein incompetence, phlebitis, migraines,
cellulitis, acute infections; bedridden patients; patients with uncontrolled
systemic disease such as diabetes, toxic hyperthyroidism, tuberculosis, asthma,
neoplasm, sepsis, blood dyscrasias, and acute respiratory or skin
diseases |
|
|
Warnings/Precautions |
|
Buerger's disease, peripheral arteriosclerosis, avoid extravasation; observe
for hypersensitivity/anaphylactic reaction |
|
|
Adverse
Reactions |
|
Percentage unknown: Headache, urticaria; sloughing and tissue necrosis
following extravasation; nausea, vomiting, mucosal lesions, esophageal
perforation, discoloration at the site of injection, ulceration at the site,
pain at injection site, pulmonary edema, asthma |
|
|
Drug
Interactions |
|
Chemically incompatible with heparin |
|
|
Stability |
|
Store at controlled room temperature in a well-closed container; protect from
light |
|
|
Mechanism of
Action |
|
Acts by irritation of the vein intimal endothelium |
|
|
Usual Dosage |
|
I.V.: Test dose: 0.5 mL given several hours prior to administration of larger
dose; 0.5-2 mL in each vein, maximum: 10 mL per treatment session; 3% solution
reserved for large varices |
|
|
Administration |
|
Inject slowly |
|
|
Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
No information available to require special precautions |
|
|
Dental Health:
Effects on Dental Treatment |
|
No effects or complications reported |
|
|
Patient
Information |
|
Notify physician if chest pain, shortness of breath, or heat, pain, or
tenderness in lower extremities |
|
|
Nursing
Implications |
|
Observe for signs and symptoms of embolism |
|
|
Dosage Forms |
|
Injection, as sulfate: 1% [10 mg/mL] (2 mL); 3% [30 mg/mL] (2
mL) |
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