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Sodium Tetradecyl
Pronunciation
U.S. Brand Names
Generic Available
Synonyms
Pharmacological Index
Use
Pregnancy Risk Factor
Contraindications
Warnings/Precautions
Adverse Reactions
Drug Interactions
Stability
Mechanism of Action
Usual Dosage
Administration
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Nursing Implications
Dosage Forms

Pronunciation
(SOW dee um tetra DEK il)

U.S. Brand Names
Sotradecol® Injection

Generic Available

No


Synonyms
Sodium Tetradecyl Sulfate

Pharmacological Index

Sclerosing Agent


Use

Treatment of small, uncomplicated varicose veins of the lower extremities; endoscopic sclerotherapy in the management of bleeding esophageal varices


Pregnancy Risk Factor

C


Contraindications

Arterial disease, thrombophlebitis, hypersensitivity to sodium tetradecyl or any component, valvular or deep vein incompetence, phlebitis, migraines, cellulitis, acute infections; bedridden patients; patients with uncontrolled systemic disease such as diabetes, toxic hyperthyroidism, tuberculosis, asthma, neoplasm, sepsis, blood dyscrasias, and acute respiratory or skin diseases


Warnings/Precautions

Buerger's disease, peripheral arteriosclerosis, avoid extravasation; observe for hypersensitivity/anaphylactic reaction


Adverse Reactions

Percentage unknown: Headache, urticaria; sloughing and tissue necrosis following extravasation; nausea, vomiting, mucosal lesions, esophageal perforation, discoloration at the site of injection, ulceration at the site, pain at injection site, pulmonary edema, asthma


Drug Interactions

Chemically incompatible with heparin


Stability

Store at controlled room temperature in a well-closed container; protect from light


Mechanism of Action

Acts by irritation of the vein intimal endothelium


Usual Dosage

I.V.: Test dose: 0.5 mL given several hours prior to administration of larger dose; 0.5-2 mL in each vein, maximum: 10 mL per treatment session; 3% solution reserved for large varices


Administration

Inject slowly


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Patient Information

Notify physician if chest pain, shortness of breath, or heat, pain, or tenderness in lower extremities


Nursing Implications

Observe for signs and symptoms of embolism


Dosage Forms

Injection, as sulfate: 1% [10 mg/mL] (2 mL); 3% [30 mg/mL] (2 mL)


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