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Pronunciation |
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(SOW
dee um SIT rate & SI trik AS
id) |
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U.S. Brand
Names |
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Bicitra®; Oracit® |
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Generic
Available |
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No |
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Synonyms |
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Modified Shohl's Solution |
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Pharmacological Index |
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Alkalinizing Agent |
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Use |
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Treatment of metabolic acidosis; alkalinizing agent in conditions where
long-term maintenance of an alkaline urine is desirable |
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Pregnancy Risk
Factor |
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No rating |
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Contraindications |
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Severe renal insufficiency, sodium-restricted diet |
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Warnings/Precautions |
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Conversion to bicarbonate may be impaired in patients with hepatic failure,
in shock, or who are severely ill |
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Adverse
Reactions |
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1% to 10%:
Endocrine & metabolic: Metabolic alkalosis, hyperkalemia
Gastrointestinal: Diarrhea, nausea, vomiting |
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Overdosage/Toxicology |
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Symptoms of overdose include hypokalemia, hypernatremia, tetany, seizures
Hypernatremia is resolved through the use of diuretics and free water
replacement |
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Drug
Interactions |
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Decreased effect/levels of lithium, chlorpropamide, salicylates due to
urinary alkalinization
Increased toxicity/levels of amphetamines, ephedrine, pseudoephedrine,
flecainide, quinidine, quinine due to urinary alkalinization
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Usual Dosage |
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Oral:
Adults: 15-30 mL with water after meals and at bedtime |
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Dietary
Considerations |
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Should be administered after meals to avoid laxative
effect |
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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No information available to require special precautions |
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Dental Health:
Effects on Dental Treatment |
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No effects or complications reported |
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Patient
Information |
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Take as often as directed, preferably on an empty stomach (1 hour before or 2
hours after meals) and at least 2 hours before or after any other medications.
Dilute with 4-6 ounces of chilled water. You may experience diarrhea or nausea
and vomiting; if severe, contact prescriber. Report changes in CNS status (eg,
irritability, tremors, confusion), swelling of feet or ankles, difficulty
breathing, palpitations, abdominal pain, or tarry stools. |
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Nursing
Implications |
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May be ordered as modified Shohl's solution; dilute with 30-90 mL of chilled
water to enhance taste |
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Dosage Forms |
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Solution, oral:
Oracit®: Sodium citrate 490 mg and citric acid 640 mg
per 5 mL
Polycitra®: Sodium citrate 500 mg and citric acid 334
mg with potassium citrate 550 mg per 5 mL
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