| Pronunciation |
 (SOW
dee um a SKOR
bate) |
 |
| U.S. Brand Names |
| Cenolate® |
|
| Generic Available |
|
Yes |
|
| Pharmacological Index |
|
Vitamin, Water Soluble |
|
| Use |
|
Dental and Medical: Prevention and treatment of scurvy and to acidify urine |
|
| Pregnancy Risk Factor |
|
C |
|
| Contraindications |
|
Large doses during pregnancy |
|
| Warnings/Precautions |
|
Use with caution in diabetics, patients with renal calculi, and those on sodium-restricted diets |
|
| Adverse Reactions |
|
1% to 10%: Gastrointestinal: Diarrhea Local: Soreness at injection site Renal: Precipitation of cystine, oxalate, or urate renal stones |
|
| Drug Interactions |
|
No data reported |
|
| Pharmacodynamics/Kinetics |
|
Therapeutic serum levels: 0.4-1.5 mg/dL Time to peak serum concentration: Oral: Within 2-3 hours |
|
| Usual Dosage |
|
Oral, I.V., S.C.: Daily protective requirement: 30 mg Treatment: 100-300 mg/day (75-100 mg in premature infants) Children: Scurvy: 100-300 mg/day in divided doses for at least 2 weeks Urinary acidification: 500 mg every 6-8 hours Dietary supplement: 35-45 mg/day Adults: Scurvy: 100-250 mg 1-2 times/day for at least 2 weeks Urinary acidification: 4-12 g/day in divided doses Dietary supplement: 50-60 mg/day (RDA: 60 mg) Prevention and treatment of cold: 1-3 g/day |
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| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
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| Dental Health: Effects on Dental Treatment |
|
No effects or complications reported |
|
| Patient Information |
|
Do not exceed recommended daily allowance |
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| Nursing Implications |
|
Do not exceed recommended daily allowance |
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| Dosage Forms |
|
Crystals: 1020 mg per 1/4 teaspoonful [ascorbic acid 900 mg] Injection: 250 mg/mL [ascorbic acid 222 mg/mL] (30 mL); 562.5 mg/mL [ascorbic acid 500 mg/mL] (1 mL, 2 mL) Tablet: 585 mg [ascorbic acid 500 mg] |
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