| Pronunciation |
 (se
LEE nee
um) |
 |
| Generic Available |
|
Yes |
|
| Pharmacological Index |
|
Trace Element, Parenteral |
|
| Use |
|
Trace metal supplement |
|
| Pregnancy Risk Factor |
|
C |
|
| Contraindications |
|
Known hypersensitivity to selenium or any component |
|
| Adverse Reactions |
|
1% to 10%: Dermatologic: Alopecia or hair discoloration Gastrointestinal: Vomiting following long-term use on damaged skin; abdominal pain, garlic breath Local: Irritation Neuromuscular & skeletal: Tremor Miscellaneous: Diaphoresis |
|
| Overdosage/Toxicology |
|
Symptoms of overdose include nausea, vomiting, diarrhea |
|
| Drug Interactions |
|
No data reported |
|
| Mechanism of Action |
|
Part of glutathione peroxidase which protects cell components from oxidative damage due to peroxidases produced in cellular metabolism |
|
| Pharmacodynamics/Kinetics |
|
Elimination: Urine, feces, lungs, skin |
|
| Usual Dosage |
|
I.V. in TPN solutions: Adults: Metabolically stable: 20-40 mcg/day Deficiency from prolonged TPN support: 100 mcg/day for 24 and 21 days |
|
| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
|
| Dental Health: Effects on Dental Treatment |
|
No effects or complications reported |
|
| Patient Information |
|
For external use only; notify physician if condition persists or worsens; avoid contact with eyes |
|
| Dosage Forms |
|
Injection: 40 mcg/mL (10 mL, 30 mL) |
|
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|
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