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Pronunciation |
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(rue
BEL a & mumpz vak SEENS, kom
BINED) |
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U.S. Brand
Names |
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Biavax®
II |
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Generic
Available |
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No |
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Pharmacological Index |
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Vaccine |
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Use |
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Promote active immunity to rubella and mumps by inducing production of
antibodies |
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Pregnancy Risk
Factor |
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C |
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Pregnancy/Breast-Feeding
Implications |
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Women who are pregnant when vaccinated or who become pregnant within 3 months
of vaccination should be counseled on the theoretical risks to the fetus. The
risk of rubella-associated malformations in these women is so small as to be
negligible. MMR is the vaccine of choice if recipients are likely to be
susceptible to measles or mumps as well as to rubella. |
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Contraindications |
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Known hypersensitivity to neomycin, eggs; children <1 year, pregnant
women, primary immunodeficient patients, patients receiving immunosuppressant
drugs except corticosteroids |
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Warnings/Precautions |
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Women planning on becoming pregnant in the next 3 months should not be
vaccinated |
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Adverse
Reactions |
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All serious adverse reactions must be reported to the U.S. Department of
Health and Human Services (DHHS) Vaccine Adverse Event Reporting System (VAERS)
1-800-822-7967.
Dermatologic: Local tenderness and erythema, urticaria, rash
Neuromuscular & skeletal: Arthralgia
1% to 10%:
Central nervous system: Malaise, moderate fever, headache
Gastrointestinal: Sore throat
Miscellaneous: Lymphadenopathy
<1%: High fever (>103°F), encephalitis,
polyneuropathy, erythema multiforme, optic neuritis, hypersensitivity, allergic
reactions to the vaccine |
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Drug
Interactions |
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Whole blood, interferon immune globulin, radiation therapy, and
immunosuppressive drugs (eg, corticosteroids) may result in insufficient
response to immunization; may temporarily depress tuberculin skin test
sensitivity and reduce the seroconversion. DTP, OPV, MMR, Hib, and hepatitis B
may be given concurrently; other virus vaccine administration should be
separated by greater than or equal to 1 month. |
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Stability |
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Refrigerate, discard unused portion within 8 hours, protect from
light |
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Usual Dosage |
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Children >12 months (preferably at 15 months) and Adults: 1 vial (0.5 mL)
in outer aspect of the upper arm; children vaccinated before 12 months of age
should be revaccinated |
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Administration |
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Administer S.C. only |
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Test
Interactions |
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Temporary suppression of TB skin test |
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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No information available to require special precautions |
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Dental Health:
Effects on Dental Treatment |
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No effects or complications reported |
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Patient
Information |
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Patient may experience burning or stinging at the injection site; joint pain
usually occurs 1-10 weeks after vaccination and persists 1-3
days |
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Nursing
Implications |
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Children immunized before 12 months of age should be
reimmunized |
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Dosage Forms |
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Injection (mixture of 2 viruses):
2. Jeryl Lynn (B level) mumps strain grown cell cultures of chick embryo
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References |
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Gardner P and Schaffner W, "Immunization of Adults," N Engl J Med,
1993, 328(17):1252-8. |
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