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Rimexolone
Pronunciation
U.S. Brand Names
Generic Available
Pharmacological Index
Use
Pregnancy Risk Factor
Contraindications
Warnings/Precautions
Adverse Reactions
Overdosage/Toxicology
Mechanism of Action
Pharmacodynamics/Kinetics
Usual Dosage
Monitoring Parameters
Mental Health: Effects on Mental Status
Mental Health: Effects on Psychiatric Treatment
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Dosage Forms

Pronunciation
(ri MEKS oh lone)

U.S. Brand Names
Vexol® Ophthalmic Suspension

Generic Available

No


Pharmacological Index

Corticosteroid, Ophthalmic


Use

Treatment of inflammation after ocular surgery and the treatment of anterior uveitis


Pregnancy Risk Factor

C


Contraindications

Fungal, viral, or untreated pus-forming bacterial ocular infections; hypersensitivity to any component


Warnings/Precautions

Prolonged use has been associated with the development of corneal or scleral perforation and posterior subcapsular cataracts; may mask or enhance the establishment of acute purulent untreated infections of the eye; effectiveness and safety have not been established in children


Adverse Reactions

1% to 10%: Ocular: Temporary mild blurred vision

<1%: Stinging, burning eyes, corneal thinning, increased intraocular pressure, glaucoma, damage to the optic nerve, defects in visual activity, cataracts, secondary ocular infection


Overdosage/Toxicology

Systemic toxicity is unlikely from the ophthalmic preparation


Mechanism of Action

Decreases inflammation by suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability


Pharmacodynamics/Kinetics

Absorption: Through aqueous humor

Metabolism: Any drug absorbed is metabolized in the liver

Elimination: By the kidneys and feces


Usual Dosage

Adults: Ophthalmic: Instill 1 drop in conjunctival sac 2-4 times/day up to every 4 hours; may use every 1-2 hours during first 1-2 days


Monitoring Parameters

Intraocular pressure and periodic examination of lens (with prolonged use)


Mental Health: Effects on Mental Status

None reported


Mental Health: Effects on Psychiatric Treatment

None reported


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Patient Information

Shake well before using, do not touch dropper to the eye


Dosage Forms

Suspension, ophthalmic: 1% (5 mL, 10 mL)


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