|
Pronunciation |
|
(ri
MEKS oh
lone) |
|
|
U.S. Brand
Names |
|
Vexol® Ophthalmic
Suspension |
|
|
Generic
Available |
|
No |
|
|
Pharmacological Index |
|
Corticosteroid, Ophthalmic |
|
|
Use |
|
Treatment of inflammation after ocular surgery and the treatment of anterior
uveitis |
|
|
Pregnancy Risk
Factor |
|
C |
|
|
Contraindications |
|
Fungal, viral, or untreated pus-forming bacterial ocular infections;
hypersensitivity to any component |
|
|
Warnings/Precautions |
|
Prolonged use has been associated with the development of corneal or scleral
perforation and posterior subcapsular cataracts; may mask or enhance the
establishment of acute purulent untreated infections of the eye; effectiveness
and safety have not been established in children |
|
|
Adverse
Reactions |
|
1% to 10%: Ocular: Temporary mild blurred vision
<1%: Stinging, burning eyes, corneal thinning, increased intraocular
pressure, glaucoma, damage to the optic nerve, defects in visual activity,
cataracts, secondary ocular infection |
|
|
Overdosage/Toxicology |
|
Systemic toxicity is unlikely from the ophthalmic
preparation |
|
|
Mechanism of
Action |
|
Decreases inflammation by suppression of migration of polymorphonuclear
leukocytes and reversal of increased capillary permeability |
|
|
Pharmacodynamics/Kinetics |
|
Absorption: Through aqueous humor
Metabolism: Any drug absorbed is metabolized in the liver
Elimination: By the kidneys and feces |
|
|
Usual Dosage |
|
Adults: Ophthalmic: Instill 1 drop in conjunctival sac 2-4 times/day up to
every 4 hours; may use every 1-2 hours during first 1-2
days |
|
|
Monitoring
Parameters |
|
Intraocular pressure and periodic examination of lens (with prolonged
use) |
|
|
Mental Health: Effects
on Mental Status |
|
None reported |
|
|
Mental Health:
Effects on Psychiatric
Treatment |
|
None reported |
|
|
Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
No information available to require special precautions |
|
|
Dental Health:
Effects on Dental Treatment |
|
No effects or complications reported |
|
|
Patient
Information |
|
Shake well before using, do not touch dropper to the eye |
|
|
Dosage Forms |
|
Suspension, ophthalmic: 1% (5 mL, 10
mL) |
|
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|