| Pronunciation |
 (rah
WOOL fee a ser pen TEEN
ah) |
 |
| U.S. Brand Names |
| Raudixin®; Rauverid®; Wolfina® |
|
| Generic Available |
|
Yes |
|
| Synonyms |
| Whole Root Rauwolfia |
|
| Pharmacological Index |
|
Rauwolfia Alkaloid |
|
| Use |
|
Mild essential hypertension; relief of agitated psychotic states |
|
| Pregnancy Risk Factor |
|
C |
|
| Contraindications |
|
Any ulcerative condition; gallstones; mental depression; electroshock therapy; hypersensitivity to rauwolfia serpentina or any component |
|
| Adverse Reactions |
|
Cardiovascular: Hypotension, tachycardia, flushing Central nervous system: Drowsiness, fatigue, CNS depression, coma, parkinsonism, hypothermia Endocrine & metabolic: Sodium and water retention, gynecomastia, galactorrhea Gastrointestinal: Abdominal cramps, nausea, vomiting, gastric acid secretion (increased), dry mouth, diarrhea Ocular: Miosis, conjunctival flushing Respiratory: Nasal congestion |
|
| Drug Interactions |
|
Use lower doses with diuretic treatment or other antihypertensive use |
|
| Stability |
|
Protect from light |
|
| Usual Dosage |
|
Adults: Oral: 200-400 mg/day in 2 divided doses |
|
| Dietary Considerations |
|
May be administered with food or milk to decrease GI distress |
|
| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
|
| Dental Health: Effects on Dental Treatment |
|
No effects or complications reported |
|
| Patient Information |
|
Take with food or milk; impotency is reversible; notify physician if a weight gain of more than 5 pounds has taken place during therapy; may cause drowsiness |
|
| Nursing Implications |
|
Monitor blood pressure (standing and sitting/supine); diarrhea, weakness, mental changes |
|
| Dosage Forms |
|
Tablet: 50 mg, 100 mg |
|
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