| |||
 | |||
 |
Ginkgo Biloba | ||
|
Licorice | ||
| |||
| |||
| |||
|
Calcium | ||
|
Vitamin D | ||
| |||
| Pronunciation |
 (kwin
ETH a
zone) |
 |
| U.S. Brand Names |
| Hydromox® |
|
| Generic Available |
|
No |
|
| Pharmacological Index |
|
Diuretic, Thiazide |
|
| Use |
|
Adjunctive therapy in treatment of edema and hypertension |
|
| Pregnancy Risk Factor |
|
D |
|
| Contraindications |
|
Anuria; hypersensitivity to sulfonamide-derived drugs |
|
| Adverse Reactions |
|
1% to 10%: Endocrine & metabolic: Hypokalemia |
|
| Drug Interactions |
|
Decreased effect: Thiazides may decrease the effect of anticoagulants, antigout agents, sulfonylureas Bile acid sequestrants, methenamine, and NSAIDs may decrease the effect of the thiazides Increased effect: Thiazides may increase the toxicity of allopurinol, anesthetics, antineoplastics, calcium salts, diazoxide, digitalis, lithium, loop diuretics, methyldopa, nondepolarizing muscle relaxants, vitamin D; amphotericin B and anticholinergics may increase the toxicity of thiazides |
|
| Mechanism of Action |
|
Quinethazone is a quinazoline derivative which increases the renal excretion of sodium and chloride and an accompanying volume of water due to inhibition of the tubular mechanism of electrolyte reabsorption. |
|
| Pharmacodynamics/Kinetics |
|
Onset of action: 2 hours Duration: 18-24 hours |
|
| Usual Dosage |
|
Adults: Oral: 50-100 mg once daily; usual maximum: 200 mg/day |
|
| Dietary Considerations |
|
May be administered with food or milk |
|
| Mental Health: Effects on Mental Status |
|
May cause drowsiness |
|
| Mental Health: Effects on Psychiatric Treatment |
|
May rarely cause agranulocytosis; use caution with clozapine and carbamazepine; may decrease lithium clearance resulting in an increase in serum lithium levels and potential lithium toxicity; monitor serum lithium levels |
|
| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
|
| Dental Health: Effects on Dental Treatment |
|
No effects or complications reported |
|
| Patient Information |
|
May be taken with food or milk; take early in day to avoid nocturia; take the last dose of multiple doses no later than 6 PM unless instructed otherwise. A few people who take this medication become more sensitive to sunlight and may experience skin rash, redness, itching, or severe sunburn, especially if sun block SPF greater than or equal to 15 is not used on exposed skin areas. |
|
| Nursing Implications |
|
Administer early in day to avoid nocturia; administer the last dose of multiple doses no later than 6 PM unless instructed otherwise. A few people who take this medication become more sensitive to sunlight and may experience skin rash, redness, itching, or severe sunburn, especially if sun block SPF 15 or higher is not used on exposed skin areas. |
|
| Dosage Forms |
|
Tablet: 50 mg |
|
|
|
Copyright © 1978-2000 Lexi-Comp Inc. All Rights Reserved
