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Pronunciation |
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(proe
PAR a kane & FLURE e
seen) |
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U.S. Brand
Names |
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Fluoracaine®
Ophthalmic |
|
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Generic
Available |
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Yes |
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Pharmacological Index |
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Diagnostic Agent; Local Anesthetic |
|
|
Use |
|
Anesthesia for tonometry, gonioscopy; suture removal from cornea; removal of
corneal foreign body; cataract extraction, glaucoma surgery |
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Pregnancy Risk
Factor |
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C |
|
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Contraindications |
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Known hypersensitivity to proparacaine or fluorescein or any component or
ester-type local anesthetics |
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Warnings/Precautions |
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Use with caution in patients with cardiac disease, hyperthyroidism; for
topical ophthalmic use only; prolonged use not recommended |
|
|
Adverse
Reactions |
|
1% to 10%: Local: Burning, stinging of eye
<1%: Allergic contact dermatitis, irritation, sensitization, erosion of
the corneal epithelium, conjunctival congestion and hemorrhage, keratitis,
iritis, corneal opacification |
|
|
Drug
Interactions |
|
No data reported |
|
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Stability |
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Store in tight, light-resistant containers |
|
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Mechanism of
Action |
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Prevents initiation and transmission of impulse at the nerve cell membrane by
decreasing ion permeability through stabilizing |
|
|
Pharmacodynamics/Kinetics |
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Onset of action: Within 20 seconds of instillation
Duration: 15-20 minutes |
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Usual Dosage |
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Ophthalmic surgery: Children and Adults: Instill 1 drop in each eye every
5-10 minutes for 5-7 doses
Tonometry, gonioscopy, suture removal: Adults: Instill 1-2 drops in each eye
just prior to procedure |
|
|
Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
No information available to require special precautions |
|
|
Dental Health:
Effects on Dental Treatment |
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No effects or complications reported |
|
|
Patient
Information |
|
May slow wound healing; use sparingly, avoid touching or rubbing the eye
until anesthesia has worn off |
|
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Nursing
Implications |
|
Do not use if discolored; protect eye from irritating chemicals, foreign
bodies, and blink reflex; use eye patch if necessary |
|
|
Dosage Forms |
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Solution: Proparacaine hydrochloride 0.5% and fluorescein sodium 0.25% (2 mL,
5 mL) |
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