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Prednicarbate
Pronunciation
U.S. Brand Names
Generic Available
Pharmacological Index
Use
Pregnancy Risk Factor
Contraindications
Warnings/Precautions
Adverse Reactions
Drug Interactions
Mechanism of Action
Usual Dosage
Monitoring Parameters
Mental Health: Effects on Mental Status
Mental Health: Effects on Psychiatric Treatment
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Nursing Implications
Dosage Forms
References

Pronunciation
(PRED ni kar bate)

U.S. Brand Names
Dermatop®

Generic Available

No


Pharmacological Index

Corticosteroid, Topical


Use

Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses (medium potency topical corticosteroid)


Pregnancy Risk Factor

C


Contraindications

Hypersensitivity to prednicarbate or any component; fungal, viral, or tubercular skin lesions, herpes simplex or zoster


Warnings/Precautions

Systemic absorption of topical corticosteroids has produced reversible HPA axis suppression. This is more likely to occur when the preparation is used on large surface or denuded areas for prolonged periods of time or with an occlusive dressing.


Adverse Reactions

1% to 10%: Dermatologic: Skin atrophy, shininess, thinness, mild telangiectasia

<1%: Pruritus, edema, urticaria, burning, allergic contact dermatitis and rash, folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, secondary infection, striae, miliaria, paresthesia


Drug Interactions

No data reported


Mechanism of Action

Topical corticosteroids have anti-inflammatory, antipruritic, vasoconstrictive, and antiproliferative actions


Usual Dosage

Adults: Topical: Apply a thin film to affected area twice daily. Therapy should be discontinued when control is achieved; if no improvement is seen, reassessment of diagnosis may be necessary.


Monitoring Parameters

Relief of symptoms


Mental Health: Effects on Mental Status

None reported


Mental Health: Effects on Psychiatric Treatment

None reported


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Patient Information

Use only as prescribed and for no longer than the period prescribed; apply sparingly in a thin film and rub in lightly; avoid contact with eyes; do not apply to the face, underarms, or groin areas; notify physician if condition persists or worsens


Nursing Implications

Use sparingly


Dosage Forms

Cream: 0.1% (15 g, 60 g)


References

Rumbaugh MM, "High Potency Topical Corticosteroids," US Pharm, 1993, 18(6):30-41.


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