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Pronunciation |
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(PRED
ni kar
bate) |
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U.S. Brand
Names |
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Dermatop® |
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Generic
Available |
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No |
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Pharmacological Index |
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Corticosteroid, Topical |
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|
Use |
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Relief of the inflammatory and pruritic manifestations of
corticosteroid-responsive dermatoses (medium potency topical
corticosteroid) |
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Pregnancy Risk
Factor |
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C |
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Contraindications |
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Hypersensitivity to prednicarbate or any component; fungal, viral, or
tubercular skin lesions, herpes simplex or zoster |
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Warnings/Precautions |
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Systemic absorption of topical corticosteroids has produced reversible HPA
axis suppression. This is more likely to occur when the preparation is used on
large surface or denuded areas for prolonged periods of time or with an
occlusive dressing. |
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Adverse
Reactions |
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1% to 10%: Dermatologic: Skin atrophy, shininess, thinness, mild
telangiectasia
<1%: Pruritus, edema, urticaria, burning, allergic contact dermatitis and
rash, folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis,
secondary infection, striae, miliaria, paresthesia |
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Drug
Interactions |
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No data reported |
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Mechanism of
Action |
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Topical corticosteroids have anti-inflammatory, antipruritic,
vasoconstrictive, and antiproliferative actions |
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Usual Dosage |
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Adults: Topical: Apply a thin film to affected area twice daily. Therapy
should be discontinued when control is achieved; if no improvement is seen,
reassessment of diagnosis may be necessary. |
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Monitoring
Parameters |
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Relief of symptoms |
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Mental Health: Effects
on Mental Status |
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None reported |
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Mental Health:
Effects on Psychiatric
Treatment |
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None reported |
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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No information available to require special precautions |
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Dental Health:
Effects on Dental Treatment |
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No effects or complications reported |
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Patient
Information |
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Use only as prescribed and for no longer than the period prescribed; apply
sparingly in a thin film and rub in lightly; avoid contact with eyes; do not
apply to the face, underarms, or groin areas; notify physician if condition
persists or worsens |
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Nursing
Implications |
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Use sparingly |
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Dosage Forms |
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Cream: 0.1% (15 g, 60 g) |
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References |
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Rumbaugh MM, "High Potency Topical Corticosteroids," US Pharm, 1993,
18(6):30-41. |
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