| Pronunciation |
 (poe
TASS ee um SIT
rate) |
 |
| U.S. Brand Names |
| Urocit®-K |
|
| Generic Available |
|
Yes |
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| Canadian Brand Names |
| K-Lyte® |
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| Pharmacological Index |
|
Alkalinizing Agent |
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| Use |
|
Prevention of uric acid nephrolithiasis; prevention of calcium renal stones in patients with hypocitraturia; urinary alkalinizer when sodium citrate is contraindicated |
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| Pregnancy Risk Factor |
|
No rating |
|
| Contraindications |
|
Severe renal insufficiency; sodium-restricted diet (sodium citrate); untreated Addison's disease; severe myocardial damage; acute dehydration; patients with hyperkalemia; patients with delayed gastric emptying, esophageal compression, intestinal obstruction or stricture, or those taking anticholinergic medication; patients with active urinary tract infection |
|
| Warnings/Precautions |
|
Use caution in patients with congestive heart failure, hypertension, edema, or any condition sensitive to sodium or potassium intake. Citrate is converted to bicarbonate in the liver. This conversion may be blocked in patients who are severely ill, in shock, or in hepatic failure. Use caution with potassium-sparing diuretics and drugs that slow GI transit time. |
|
| Adverse Reactions |
|
>10%: Gastrointestinal: Diarrhea, nausea, stomach pain, flatulence, vomiting (oral) 1% to 10%: Cardiovascular: Bradycardia Endocrine & metabolic: Hyperkalemia, metabolic alkalosis in patients with severe renal failure Neuromuscular & skeletal: Weakness Respiratory: Dyspnea <1% (Limited to important or life-threatening symptoms): Chest pain, arrhythmias, heart block, hypotension |
|
| Usual Dosage |
|
Adults: Oral: 10-20 mEq 3 times/day with meals up to 100 mEq/day |
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| Dietary Considerations |
|
May be administered with meals |
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| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
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| Dental Health: Effects on Dental Treatment |
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No effects or complications reported |
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| Patient Information |
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Take as directed; do not take more than directed. Swallow tablet whole with full glass of water or juice and stir before sipping slowly, with or after meals (do not take on an empty stomach). Take any antacids 2 hours before or after potassium. Consult prescriber about advisability of increasing dietary potassium. Report tingling of hands or feet; unresolved nausea or vomiting; chest pain or palpitations; persistent abdominal pain; feelings of weakness, dizziness, listlessness, confusion, acute muscle weakness or cramping; blood in stool or tarry stools; or easy bruising or unusual bleeding. |
|
| Nursing Implications |
|
Swallow tablets whole with a full glass of water; intact wax matrix may appear in the feces |
|
| Dosage Forms |
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Tablet: 540 mg [5 mEq], 1080 mg [10 mEq] |
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