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Potassium Citrate and Citric Acid
Pronunciation
U.S. Brand Names
Generic Available
Synonyms
Pharmacological Index
Use
Pregnancy Risk Factor
Contraindications
Warnings/Precautions
Adverse Reactions
Usual Dosage
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Nursing Implications
Dosage Forms

Pronunciation
(poe TASS ee um SIT rate & SI trik AS id)

U.S. Brand Names
Polycitra®-K

Generic Available

No


Synonyms
Citric Acid and Potassium Citrate

Pharmacological Index

Alkalinizing Agent


Use

Treatment of metabolic acidosis; alkalinizing agent in conditions where long-term maintenance of an alkaline urine is desirable


Pregnancy Risk Factor

A


Contraindications

Severe renal insufficiency, oliguria or azotemia, potassium-restricted diet, untreated Addison's disease, adynamia episodica hereditaria, acute dehydration, heat cramps, anuria, severe myocardial damage, hyperkalemia from any cause


Warnings/Precautions

Use with caution in patients with congestive heart failure, hypertension, pulmonary edema, or severe renal impairment. Large doses may cause hyperkalemia and alkalosis.


Adverse Reactions

>10%: Gastrointestinal: Diarrhea, nausea, stomach pain, flatulence, vomiting (oral)

1% to 10%:

Cardiovascular: Bradycardia

Endocrine & metabolic: Hyperkalemia, metabolic alkalosis in patients with severe renal failure

Neuromuscular & skeletal: Weakness

Respiratory: Dyspnea

<1% (Limited to important or life-threatening symptoms): Chest pain, arrhythmias, heart block, hypotension


Usual Dosage

Oral:

Severe hypocitraturia: Initial: 20 mEq 3 times/day or 15 mEq 4 times/day with meals or within 30 minutes after meals; do not exceed 100 mEq/day


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Patient Information

Take as directed; do not take more than directed. Dilute crystals or solution in 4-6 ounces of juice or water; stir and drink. Swallow tablet whole with full glass of water or juice and stir before sipping slowly, with or after meals (do not take on an empty stomach). Take any antacids 2 hours before or after potassium. Consult prescriber about advisability of increasing dietary potassium. Report tingling of hands or feet; unresolved nausea or vomiting; chest pain or palpitations; persistent abdominal pain; feelings of weakness, dizziness, listlessness, confusion, acute muscle weakness or cramping; blood in stool or tarry stools; or easy bruising or unusual bleeding.


Nursing Implications

Potassium citrate 3.4 mmol/5 mL and citric acid 1.6 mmol/5 mL = total of 5.0 mmol/5 mL citrate content


Dosage Forms

Crystals for reconstitution: Potassium citrate 3300 mg and citric acid 1002 mg per packet

Solution, oral: Potassium citrate 1100 mg and citric acid 334 mg per 5 mL


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