|
Pronunciation |
|
(pye
loe KAR peen & ep i NEF
rin) |
|
|
U.S. Brand
Names |
|
E-Pilo-x® Ophthalmic;
PxEx®
Ophthalmic |
|
|
Generic
Available |
|
No |
|
|
Canadian Brand
Names |
|
E-Pilo® |
|
|
Synonyms |
|
Epinephrine and Pilocarpine |
|
|
Pharmacological Index |
|
Ophthalmic Agent, Antiglaucoma; Ophthalmic Agent, Miotic |
|
|
Use |
|
Treatment of glaucoma; counter effect of cycloplegics |
|
|
Pregnancy Risk
Factor |
|
C |
|
|
Contraindications |
|
Hypersensitivity to pilocarpine, epinephrine, or any component; acute
inflammatory disease of anterior chamber |
|
|
Adverse
Reactions |
|
1% to 10%:
Central nervous system: Headache
Dermatologic: Stinging, itching
Gastrointestinal: Salivation
Hematologic: Vitreous hemorrhages
Ocular: Miosis, ciliary spasm, blurred vision, retinal detachment,
lacrimation, photophobia, acute iritis
Miscellaneous: Hypersensitivity reactions |
|
|
Stability |
|
Store at 8°C to 30°C
(46°F to 86°F); keep tightly closed;
do not use solution if it is brown or contains a precipitate; protect from heat
and light |
|
|
Usual Dosage |
|
Instill 1-2 drops up to 6 times/day |
|
|
Mental Health: Effects
on Mental Status |
|
None reported |
|
|
Mental Health:
Effects on Psychiatric
Treatment |
|
Pilocarpine may antagonize the effects of anticholinergic and produce cardiac
conduction abnormalities in patients receiving
beta-blockers |
|
|
Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
No information available to require special precautions |
|
|
Dental Health:
Effects on Dental Treatment |
|
No effects or complications reported |
|
|
Patient
Information |
|
See individual agents. Pregnancy/breast-feeding precautions: Inform
prescriber if you are or intend to get pregnant. Consult prescriber if
breast-feeding. |
|
|
Nursing
Implications |
|
Usually causes difficulty in dark adaptation; advise patients to use caution
while night driving or performing hazardous tasks in poor
illumination |
|
|
Dosage Forms |
|
Solution, ophthalmic: Epinephrine bitartrate 1% and pilocarpine hydrochloride
1%, 2%, 3%, 4%, 6% (15 mL) |
|
Copyright © 1978-2000 Lexi-Comp Inc. All Rights Reserved
|