No

Analgesic, Combination (Narcotic)

Relief of moderate to severe pain; sedative prior to surgery; supplement to surgical anesthesia

D/C (Talacen®)

Hypersensitivity to pentazocine, aspirin, or acetaminophen; pregnancy

Contains sodium metasulfite as sulfite that may cause allergic-type reactions; potential for elevating CSF pressure due to respiratory effects which may be exaggerated in presence of head injury, intracranial lesions, or pre-existing increase in intracranial lesions. May experience hallucinations, disorientation, and confusion. May cause psychological and physical dependence. Use with caution in patients with myocardial infarction who have nausea or vomiting, patients with respiratory depression, severely limited respiratory reserve, severe bronchial asthma, other obstructive respiratory conditions or cyanosis, impaired renal or hepatic function, patients prone to seizures. Talwin®-ASA: Use with caution in patients with peptic ulcer or patients on anticoagulation therapy.

>10%:

Central nervous system: Fatigue, drowsiness, false sense of well-being

Gastrointestinal: Nausea, vomiting

1% to 10%:

Cardiovascular: Tachycardia or bradycardia, hypertension or hypotension

Central nervous system: Nervousness, headache, restlessness, malaise, dizziness

Dermatologic: Rash, urticaria

Gastrointestinal: Dry mouth, biliary spasm, constipation

Genitourinary: Ureteral spasms, decreased urination

Local: Pain at injection site

Neuromuscular & skeletal: Weakness

Ocular: Blurred vision

Respiratory: Dyspnea, shortness of breath

Miscellaneous: Histamine release

<1% (Limited to important or life-threatening symptoms): Convulsions, increased intracranial pressure

Adults: Oral: 2 tablets 3-4 times/day

No information available to require special precautions

No effects or complications reported

If self-administered, use exactly as directed (do not increase dose or frequency); may cause physical and/or psychological dependence. Take with food or milk. While using this medication, do not use alcohol and other prescription or OTC medications (especially sedatives, tranquilizers, antihistamines, or pain medications) without consulting prescriber. Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). May cause hypotension, dizziness, drowsiness, confusion, or nervousness (use caution when driving, climbing stairs, or changing position - rising from sitting or lying to standing, or when engaging in tasks requiring alertness until response to drug is known); nausea, dry mouth, decreased appetite, or gastric distress (frequent mouth care, frequent sips of fluids, chewing gum, or sucking lozenges may help); constipation (increased exercise, fluids, or dietary fruit and fiber may help - if constipation remains an unresolved problem, consult prescriber about use of stool softeners). Report chest pain, rapid heartbeat or palpitations; persistent dizziness; change in mental status; shortness of breath or difficulty breathing; unusual bleeding (stool, mouth, urine) or bruising; unusual fatigue and weakness; pain on urination; change in elimination patterns or change in color of urine or stool; or unresolved nausea or vomiting. Pregnancy/breast-feeding precautions: Inform prescriber if you are or intend to be pregnant. Do not breast-feed.

Observe patient for excessive sedation, respiratory depression, implement safety measures, assist with ambulation; observe for narcotic withdrawal

Tablet:

Talacen®: Pentazocine hydrochloride 25 mg and acetaminophen 650 mg

Talwin® Compound: Pentazocine hydrochloride 12.5 mg and aspirin 325 mg