| Pronunciation |
 (pen
ta GAS
trin) |
 |
| U.S. Brand Names |
| Peptavlon® |
|
| Generic Available |
|
No |
|
| Pharmacological Index |
|
Diagnostic Agent |
|
| Use |
|
Evaluate gastric acid secretory function in pernicious anemia, gastric carcinoma; in suspected duodenal ulcer or Zollinger-Ellison tumor |
|
| Pregnancy Risk Factor |
|
C |
|
| Adverse Reactions |
|
>10%: Gastrointestinal: Abdominal pain, desire to defecate, nausea, vomiting 1% to 10%: Cardiovascular: Flushing, tachycardia, palpitations, hypotension, faintness Central nervous system: Dizziness, headache Respiratory: Dyspnea <1%: Miscellaneous: Allergic reactions |
|
| Stability |
|
Refrigerate |
|
| Mechanism of Action |
|
Excites the oxyntic cells of the stomach to secrete to their maximum capacity similar to the naturally occurring hormone, gastrin |
|
| Pharmacodynamics/Kinetics |
|
Absorption: I.M., S.C.: Well absorbed Serum half-life: 1 minute |
|
| Usual Dosage |
|
Adults: I.V. infusion: 0.1-12 mcg/kg/hour in 0.9% sodium chloride |
|
| Dietary Considerations |
|
Patient should fast from food and liquids overnight and be instructed not to take antacids on the morning of the test nor drugs that inhibit gastric secretion |
|
| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
|
| Dental Health: Effects on Dental Treatment |
|
No effects or complications reported |
|
| Patient Information |
|
Fast from food and liquids overnight and do not take antacids on the morning of the test nor drugs that inhibit gastric secretion |
|
| Nursing Implications |
|
Refrigerate |
|
| Dosage Forms |
|
Injection: 0.25 mg/mL (2 mL) |
|
|
|
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