| Pronunciation |
 (oks
i fen SYE kli
meen) |
 |
| U.S. Brand Names |
| Daricon® |
|
| Generic Available |
|
No |
|
| Synonyms |
| Oxyphencyclimine Hydrochloride |
|
| Pharmacological Index |
|
Anticholinergic Agent; Antispasmodic Agent, Gastrointestinal |
|
| Use |
|
Adjunctive treatment of peptic ulcer |
|
| Pregnancy Risk Factor |
|
C |
|
| Contraindications |
|
Angle-closure glaucoma; obstructive GI tract or uropathy; severe ulcerative colitis; myasthenia gravis; intestinal atony |
|
| Adverse Reactions |
|
>10%: Dermatologic: Dry skin Gastrointestinal: Constipation, dry throat, xerostomia Respiratory: Dry nose Miscellaneous: Decreased diaphoresis 1% to 10%: Dermatologic: Increased sensitivity to light Gastrointestinal: Dysphagia |
|
| Drug Interactions |
|
Increased anticholinergic side effects by amantadine; decreased phenothiazines, antiparkinsonian drugs, Haldol® effects |
|
| Usual Dosage |
|
Children >12 years and Adults: Oral: 10 mg twice daily or 5 mg 3 times/day |
|
| Mental Health: Effects on Mental Status |
|
May cause drowsiness, nervousness, confusion, amnesia, or insomnia |
|
| Mental Health: Effects on Psychiatric Treatment |
|
Concurrent use with psychotropics may alter their clinical effects, but it is not likely to be of significance, however, side effects may be additive especially anticholinergics (drowsiness, dry mouth) |
|
| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
|
| Dental Health: Effects on Dental Treatment |
|
>10% of patients experience dry mouth |
|
| Patient Information |
|
May cause drowsiness; avoid alcohol; may impair coordination and judgment may cause blurred vision |
|
| Dosage Forms |
|
Tablet, as hydrochloride: 10 mg |
|
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