|
Pronunciation |
|
(nee
oh MYE sin, pol i MIKS in bee,
& pred NIS oh lone) |
|
|
U.S. Brand
Names |
|
Poly-Pred® Ophthalmic
Suspension |
|
|
Generic
Available |
|
Yes |
|
|
Synonyms |
|
polymyxin b, neomycin, and prednisolone; prednisolone, neomycin, and polymyxin
b |
|
|
Pharmacological Index |
|
Antibiotic/Corticosteroid, Ophthalmic |
|
|
Use |
|
Steroid-responsive inflammatory ocular condition in which bacterial infection
or a risk of bacterial ocular infection exists |
|
|
Pregnancy Risk
Factor |
|
C |
|
|
Adverse
Reactions |
|
1% to 10%:
Ocular: Increased intraocular pressure, glaucoma, optic nerve damage,
cataracts, conjunctival sensitization |
|
|
Drug
Interactions |
|
No data reported |
|
|
Mechanism of
Action |
|
Refer to individual monographs |
|
|
Pharmacodynamics/Kinetics |
|
Refer to individual monographs |
|
|
Usual Dosage |
|
Children and Adults: Ophthalmic: Instill 1-2 drops every 3-4 hours; acute
infections may require every 30-minute instillation initially with frequency of
administration reduced as the infection is brought under control. To treat the
lids: Instill 1-2 drops every 3-4 hours, close the eye and rub the excess on the
lids and lid margins. |
|
|
Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
No information available to require special precautions |
|
|
Dental Health:
Effects on Dental Treatment |
|
No effects or complications reported |
|
|
Patient
Information |
|
Ophthalmic: May cause sensitivity to bright light; may cause temporary
blurring of vision or stinging following administration, but discontinue product
and see physician if problems persist or increase; to use, tilt head back and
place medication in conjunctival sac and close eyes; apply light pressure on
lacrimal sac for 1 minute |
|
|
Nursing
Implications |
|
Shake suspension before using |
|
|
Dosage Forms |
|
Suspension, ophthalmic: Neomycin sulfate 0.35%, polymyxin B sulfate 10,000
units, and prednisolone acetate 0.5% per mL (5 mL, 10
mL) |
|
Copyright © 1978-2000 Lexi-Comp Inc. All Rights Reserved
|