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Look Up > Drugs > Neomycin, Polymyxin B, and Dexamethasone
Neomycin, Polymyxin B, and Dexamethasone
Pronunciation
U.S. Brand Names
Generic Available
Synonyms
Pharmacological Index
Use
Pregnancy Risk Factor
Adverse Reactions
Drug Interactions
Mechanism of Action
Pharmacodynamics/Kinetics
Usual Dosage
Administration
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Nursing Implications
Dosage Forms

Pronunciation
(nee oh MYE sin, pol i MIKS in bee, & deks a METH a sone)

U.S. Brand Names
AK-Trol®; Dexacidin®; Dexasporin®; Maxitrol®

Generic Available

Yes


Synonyms
dexamethasone, neomycin, and polymyxin b; polymyxin b, neomycin, and dexamethasone

Pharmacological Index

Antibiotic/Corticosteroid, Ophthalmic


Use

Steroid-responsive inflammatory ocular conditions in which a corticosteroid is indicated and where bacterial infection or a risk of bacterial infection exists


Pregnancy Risk Factor

C


Adverse Reactions

1% to 10%:

Ocular: Cutaneous sensitization, eye pain, development of glaucoma, cataract, increased intraocular pressure, optic nerve damage


Drug Interactions

No data reported


Mechanism of Action

Refer to individual monographs


Pharmacodynamics/Kinetics

Refer to individual monographs


Usual Dosage

Children and Adults: Ophthalmic:

Solution: Instill 1-2 drops into affected eye(s) every 3-4 hours; in severe disease, drops may be used hourly and tapered to discontinuation


Administration

Tilt head back, place medication in conjunctival sac and close eyes


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Patient Information

Notify physician if condition worsens or does not improve in 3-4 days


Nursing Implications

Shake well before using

Monitor intraocular pressure with use >10 days


Dosage Forms

Ophthalmic:

Suspension: Neomycin sulfate 3.5 mg, polymyxin B sulfate 10,000 units and dexamethasone 0.1% per mL (5 mL, 10 mL)


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