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Naphazoline and Pheniramine
Pronunciation
U.S. Brand Names
Generic Available
Synonyms
Pharmacological Index
Use
Pregnancy Risk Factor
Contraindications
Adverse Reactions
Drug Interactions
Usual Dosage
Mental Health: Effects on Mental Status
Mental Health: Effects on Psychiatric Treatment
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Nursing Implications
Dosage Forms

Pronunciation
(naf AZ oh leen & fen NIR a meen)

U.S. Brand Names
Naphcon-A® Ophthalmic [OTC]

Generic Available

No


Synonyms
Pheniramine and Naphazoline

Pharmacological Index

Ophthalmic Agent, Vasoconstrictor


Use

Topical ocular vasoconstrictor


Pregnancy Risk Factor

C


Contraindications

Hypersensitivity to naphazoline, pheniramine, or any component


Adverse Reactions

1% to 10%:

Systemic effects due to absorption:

Cardiovascular: Hypertension, cardiac irregularities

Endocrine & metabolic: Hyperglycemia


Drug Interactions

MAO inhibitors (hypertensive crisis possible)


Usual Dosage

1-2 drops every 3-4 hours


Mental Health: Effects on Mental Status

May cause nervousness or dizziness


Mental Health: Effects on Psychiatric Treatment

TCAs and MAOIs may potentiate the pressor response of decongestants; monitor for changes in response


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Patient Information

Discontinue drug and consult physician if ocular pain or visual changes occur, ocular redness or irritation, or condition worsens or persists more than 72 hours


Nursing Implications

Discontinue drug and consult physician if ocular pain or visual changes occur, ocular redness or irritation, or condition worsens or persists more than 72 hours


Dosage Forms

Solution, ophthalmic: Naphazoline hydrochloride 0.025% and pheniramine 0.3% (15 mL)


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