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Naphazoline and Antazoline
Pronunciation
U.S. Brand Names
Generic Available
Pharmacological Index
Use
Pregnancy Risk Factor
Contraindications
Adverse Reactions
Drug Interactions
Stability
Usual Dosage
Mental Health: Effects on Mental Status
Mental Health: Effects on Psychiatric Treatment
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Nursing Implications
Dosage Forms

Pronunciation
(naf AZ oh leen & an TAZ oh leen)

U.S. Brand Names
Albalon-A® Ophthalmic; Antazoline-V® Ophthalmic; Vasocon-A®[OTC] Ophthalmic

Generic Available

No


Pharmacological Index

Ophthalmic Agent, Vasoconstrictor


Use

Topical ocular congestion, irritation and itching


Pregnancy Risk Factor

C


Contraindications

Angle-closure glaucoma; hypersensitivity to naphazoline or antazoline


Adverse Reactions

1% to 10%:

Central nervous system: Nervousness, dizziness, headache

Gastrointestinal: Nausea

Local: Transient stinging

Neuromuscular & skeletal: Weakness

Ocular: Mydriasis, increased intraocular pressure, blurring of vision

Respiratory: Nasal mucosa irritation, dryness, rebound congestion

Miscellaneous: Diaphoresis


Drug Interactions

MAO inhibitors


Stability

Store in tight, light-resistant containers


Usual Dosage

1-2 drops every 3-4 hours


Mental Health: Effects on Mental Status

May cause nervousness or dizziness


Mental Health: Effects on Psychiatric Treatment

TCAs and MAOIs may potentiate the pressor response of decongestants; monitor for changes in response


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Patient Information

Do not use discolored solutions


Nursing Implications

Do not use discolored solutions


Dosage Forms

Solution: Naphazoline hydrochloride 0.05% and antazoline phosphate 0.5% (15 mL)


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