No

Hemostatic Agent

Adjunct to hemostasis when control of bleeding by ligature is ineffective or impractical

C

Closure of skin incisions, contaminated wounds

Fragments of MCH may pass through filters of blood scavenging systems, avoid reintroduction of blood from operative sites treated with MCH; after several minutes remove excess material

1% to 10%: Miscellaneous: Potentiation of infection, allergic reaction, adhesion formation

No data reported

Microfibrillar collagen hemostat is an absorbable topical hemostatic agent prepared from purified bovine corium collagen and shredded into fibrils. Physically, microfibrillar collagen hemostat yields a large surface area. Chemically, it is collagen with hydrochloric acid noncovalently bound to some of the available amino groups in the collagen molecules. When in contact with a bleeding surface, microfibrillar collagen hemostat attracts platelets which adhere to its fibrils and undergo the release phenomenon. This triggers aggregation of the platelets into thrombi in the interstices of the fibrous mass, initiating the formation of a physiologic platelet plug.

Absorption: By animal tissue in 3 months

Apply dry directly to source of bleeding

No information available to require special precautions

No effects or complications reported

Fragments of MCH may pass through filters of blood-scavenging systems; avoid reintroduction of blood from operative sites treated with MCH

Fibrous: 1 g, 5 g

Nonwoven web: 70 mm x 70 mm x 1 mm; 70 mm x 35 mm x 1 mm

Sponge: 1" x 2" (10s); 3" x 4" (10s); 9" x 10" (5s)