I.V.:
Chronic respiratory paralysis in neonates: Start 0.25-0.5 mg/kg/dose (repeat
once if paralysis is not achieved in 3 minutes); maintenance: repeat previous
dose as soon as movement is observed. The dose should be titrated to achieve a
dosage interval of 3-4 hours, then plateau at 10-20 mg/kg/24 hours
Neuromuscular blockade for surgery: Initial: 0.2-0.4 mg/kg/dose; maintenance:
0.1-0.25 mg/kg/dose every 25-90 minutes
Adults:
Surgery: Initial: 0.2-0.4 mg/kg; supplement dose: 0.5-1 mg; use of
anesthetics that potentiate effect of neuromuscular blocking drug requires less
metocurine
Electric shock therapy: 1.75-5.5 mg