| Pronunciation |
 (meth
AN tha
leen) |
 |
| U.S. Brand Names |
| Banthine® |
|
| Generic Available |
|
No |
|
| Synonyms |
| Methantheline Bromide; Methanthelinium Bromide |
|
| Pharmacological Index |
|
Anticholinergic Agent |
|
| Use |
|
Adjunctive treatment of peptic ulcer, irritable bowel syndrome, pancreatitis, ureteral and urinary bladder spasm; to reduce duodenal motility during diagnostic radiologic procedures and treatment of an uninhibited neurogenic bladder |
|
| Pregnancy Risk Factor |
|
C |
|
| Contraindications |
|
Angle-closure glaucoma; hypersensitivity to methantheline |
|
| Adverse Reactions |
|
>10%: Dermatologic: Dry skin Gastrointestinal: Constipation, xerostomia, dry throat Respiratory: Dry nose Miscellaneous: Decreased diaphoresis 1% to 10%: Gastrointestinal: Dysphagia |
|
| Usual Dosage |
|
Oral: Children: <1 year: 12.5-25 mg 4 times/day >1 year: 12.5-50 mg 4 times/day Adults: 50-100 mg every 6 hours |
|
| Mental Health: Effects on Mental Status |
|
May cause confusion, amnesia, drowsiness, nervousness, or insomnia |
|
| Mental Health: Effects on Psychiatric Treatment |
|
Concurrent use with psychotropics may produce additive sedation or dry mouth |
|
| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
|
| Dental Health: Effects on Dental Treatment |
|
>10% of patients experience dry mouth |
|
| Dosage Forms |
|
Tablet, as bromide: 50 mg |
|
|
|
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