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Pronunciation |
|
(me
PEN zoe
late) |
|
|
U.S. Brand
Names |
|
Cantil® |
|
|
Generic
Available |
|
No |
|
|
Synonyms |
|
Mepenzolate Bromide |
|
|
Pharmacological Index |
|
Anticholinergic Agent; Antispasmodic Agent,
Gastrointestinal |
|
|
Use |
|
Management of peptic ulcer disease; inhibit salivation and excessive
secretions in respiratory tract preoperatively |
|
|
Pregnancy Risk
Factor |
|
C |
|
|
Contraindications |
|
Angle-closure glaucoma; acute hemorrhage; tachycardia; hypersensitivity to
mepenzolate or any component; obstructive uropathy (ie, bladder neck obstruction
due to prostatic hypertrophy); obstructive gastrointestinal disease (ie,
pyloroduodenal stenosis, achalasia); paralytic ileus; intestinal atony of the
debilitated or elderly patient; unstable cardiovascular status in acute
hemorrhage; severe ulcerative colitis or toxic megacolon complicating ulcerative
colitis; myasthenia gravis; allergic or idiosyncratic reactions of related
compounds |
|
|
Adverse
Reactions |
|
>10%:
Gastrointestinal: Constipation, xerostomia, dry throat
Dermatologic: Dry skin
Respiratory: Dry nose
Miscellaneous: Decreased diaphoresis
1% to 10%: Gastrointestinal: Dysphagia |
|
|
Usual Dosage |
|
Adults: Oral: 25-50 mg 4 times/day with meal and at
bedtime |
|
|
Dietary
Considerations |
|
May be administered with meals |
|
|
Mental Health: Effects
on Mental Status |
|
May rarely cause confusion, amnesia, drowsiness, nervousness, or
insomnia |
|
|
Mental Health:
Effects on Psychiatric
Treatment |
|
Concurrent use with psychotropics may produce additive drowsiness or
anticholinergic side effects (dry mouth) |
|
|
Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
No information available to require special precautions |
|
|
Dental Health:
Effects on Dental Treatment |
|
>10% of patients experience dry mouth |
|
|
Dosage Forms |
|
Tablet, as bromide: 25 mg |
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