Look Up > Drugs > Medrysone
Medrysone
Pronunciation
U.S. Brand Names
Generic Available
Pharmacological Index
Use
Pregnancy Risk Factor
Contraindications
Warnings/Precautions
Adverse Reactions
Overdosage/Toxicology
Mechanism of Action
Pharmacodynamics/Kinetics
Usual Dosage
Monitoring Parameters
Mental Health: Effects on Mental Status
Mental Health: Effects on Psychiatric Treatment
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Nursing Implications
Dosage Forms

Pronunciation
(ME dri sone)

U.S. Brand Names
HMS Liquifilm®

Generic Available

No


Pharmacological Index

Corticosteroid, Ophthalmic


Use

Treatment of allergic conjunctivitis, vernal conjunctivitis, episcleritis, ophthalmic epinephrine sensitivity reaction


Pregnancy Risk Factor

C


Contraindications

Fungal, viral, or untreated pus-forming bacterial ocular infections; not for use in iritis and uveitis


Warnings/Precautions

Prolonged use has been associated with the development of corneal or scleral perforation and posterior subcapsular cataracts; may mask or enhance the establishment of acute purulent untreated infections of the eye; effectiveness and safety have not been established in children. Medrysone is a synthetic corticosteroid; structurally related to progesterone; if no improvement after several days of treatment, discontinue medrysone and institute other therapy; duration of therapy: 3-4 days to several weeks dependent on type and severity of disease; taper dose to avoid disease exacerbation.


Adverse Reactions

1% to 10%: Ocular: Temporary mild blurred vision

<1%: Stinging, burning eyes, corneal thinning, increased intraocular pressure, glaucoma, damage to the optic nerve, defects in visual activity, cataracts, secondary ocular infection


Overdosage/Toxicology

Systemic toxicity is unlikely from the ophthalmic preparation


Mechanism of Action

Decreases inflammation by suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability


Pharmacodynamics/Kinetics

Absorption: Through aqueous humor

Metabolism: Any drug absorbed is metabolized in the liver

Elimination: By the kidneys and feces


Usual Dosage

Children and Adults: Ophthalmic: Instill 1 drop in conjunctival sac 2-4 times/day up to every 4 hours; may use every 1-2 hours during first 1-2 days


Monitoring Parameters

Intraocular pressure and periodic examination of lens (with prolonged use)


Mental Health: Effects on Mental Status

None reported


Mental Health: Effects on Psychiatric Treatment

None reported


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Patient Information

For ophthalmic use only. Shake before using. Apply prescribed amount as often as directed. Wash hands before using and do not let tip of applicator touch eye or contaminate tip of applicator. Tilt head back and look upward. Gently pull down lower lid and put drop(s) in inner corner of eye. Close eye and roll eyeball in all directions. Do not blink for 1/2 minute. Apply gentle pressure to inner corner of eye for 30 seconds. Wipe away excess from skin around eye. Do not use any other eye preparation for at least 10 minutes. Do not touch tip of applicator to eye or contaminate tip of applicator. Do not share medication with anyone else. May cause sensitivity to bright light (dark glasses may help); temporary stinging or blurred vision may occur. Inform prescriber if you experience eye pain, redness, burning, watering, dryness, double vision, puffiness around eye, vision disturbances, or other adverse eye response; worsening of condition or lack of improvement within 3-4 days. Pregnancy/breast-feeding precautions: Inform prescriber if you are pregnant. Consult prescriber if breast-feeding.


Nursing Implications

Shake well before using; do not touch dropper to the eye

Monitor intraocular pressure and periodic examination of lens (with prolonged use)


Dosage Forms

Solution, ophthalmic: 1% (5 mL, 10 mL)


Copyright © 1978-2000 Lexi-Comp Inc. All Rights Reserved