No

Antibiotic, Topical; Topical Skin Product, Acne

Topical treatment of inflammatory acne vulgaris

B

Known hypersensitivity to tetracyclines or any component

Use with caution in patients allergic to formaldehyde; for external use only

>10%: Topical: Follicular staining, yellowing of the skin, burning/stinging feeling

1% to 10%: Topical: Pain, redness, skin irritation, dermatitis

No data reported

Inhibits bacterial protein synthesis by binding with the 30S and possibly the 50S ribosomal subunit(s) of susceptible bacteria; may also cause alterations in the cytoplasmic membrane

Absorption: Topical: Very little

Children >11 years and Adults: Topical: Apply generously to affected areas twice daily

None reported

None reported

No information available to require special precautions

No effects or complications reported

For external use only. Apply with gloves to thoroughly clean/dry skin until skin is wet; avoid area around eyes or mouth. Do not cover with occlusive dressing. Results make take some time to appear. May stain clothing or fabrics. You may experience transient stinging or burning after application. If skin turns yellow, washing with soap and water will remove color. Report worsening of condition; eye irritation; or skin redness, dryness, peeling, or burning that persists between applications. Breast-feeding precautions: Consult prescriber if breast-feeding.

Apply generously until skin is wet; avoid contact with eyes, nose, and mouth; stinging may occur with application, but soon stops; if skin is discolored yellow, washing will remove the color

Cream, topical, as sulfosalicylate: 1% (20 g, 45 g)