No

Antihistamine/Decongestant Combination

Temporary relief of symptoms of seasonal allergic rhinitis and nasal congestion

B

>10%:

Cardiovascular: Tachycardia

Central nervous system: Slight to moderate drowsiness, nervousness, transient stimulation, insomnia

Respiratory: Thickening of bronchial secretions

1% to 10%:

Central nervous system: Headache, fatigue, dizziness

Gastrointestinal: Appetite increase, weight gain, nausea, diarrhea, abdominal pain, dry mouth

Genitourinary: Dysuria

Neuromuscular & skeletal: Arthralgia, weakness

Respiratory: Pharyngitis

Miscellaneous: Sweating

<1%:

Cardiovascular: Edema, palpitations, hypotension

Central nervous system: Depression, sedation, paradoxical excitement, convulsions, hallucinations

Dermatologic: Angioedema, rash, photosensitivity

Genitourinary: Urinary retention

Hepatic: Hepatitis

Neuromuscular & skeletal: Myalgia, paresthesia, tremor

Ocular: Blurred vision

Respiratory: Bronchospasm, epistaxis, dyspnea

Adults: Oral: 1 tablet every 12 hours

Use with caution since pseudoephedrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response

Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution; over 10% of patients may experience dry mouth which will disappear with cessation of drug therapy

See individual agents. Breast-feeding precautions: Breast-feeding is not recommended.

Tablet: Loratadine 5 mg and pseudoephedrine sulfate 120 mg

Tablet, extended release: Loratadine 10 mg and pseudoephedrine sulfate 240 mg